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荷兰痴呆老年护理院肺炎患者治疗趋势。

Trends in treatment of pneumonia among Dutch nursing home patients with dementia.

机构信息

EMGO Institute, VU University Medical Center, Amsterdam, The Netherlands.

出版信息

J Palliat Med. 2009 Sep;12(9):789-95. doi: 10.1089/jpm.2009.0049.

Abstract

PURPOSE

To test if care to relief suffering in patients with dementia who become ill with pneumonia is improving, we compared treatments in cohorts of patients with dementia and pneumonia a decade apart.

PARTICIPANTS AND METHODS

We studied 61 nursing homes in The Netherlands between 1996-1998 and 54 nursing homes between 2006-2007, 53 of which had been in the earlier cohort. In 1996-1998, 706 patients with pneumonia and dementia were prospectively enrolled by 201 physicians and in 2006-2007, 72 patients by 69 physicians. Data collected included treatment, physician and patient characteristics, outcome, and additionally, in the 2006-2007 cohort only, physicians' perception of changes in treatment they generally provide.

RESULTS

The frequency of providing antibiotics was similar: 79% in the recent cohort versus 77% ten years earlier (p = 0.63) as was oral antibiotic treatment (91% of those receiving antibiotics versus 88%; p = 0.44). Treatment to relieve symptoms was provided more frequently in the more recent cohort. For example, antipyretics (54% versus 34%; p = 0.001), oxygen (29% versus 13%; p < 0.001), and opiates (22% versus 10%; p = 0.003). Differences were not explained by different case mix. Half of physicians (49%) stated they generally treat to relieve symptoms more frequently than before.

CONCLUSIONS

Symptom relief to Dutch patients with dementia and pneumonia is provided more frequently than a decade ago while the rate of treatment with antibiotics is unchanged. Further studies in The Netherlands and elsewhere are needed to detect if this is a general trend.

摘要

目的

为了检验对患有肺炎的痴呆症患者的痛苦护理是否有所改善,我们对比了相隔十年的两组痴呆症合并肺炎患者的治疗方法。

参与者和方法

我们研究了荷兰 1996 年至 1998 年间的 61 家养老院和 2006 年至 2007 年间的 54 家养老院,其中 53 家养老院在之前的队列中。1996 年至 1998 年间,201 名医生前瞻性地招募了 706 名患有肺炎和痴呆症的患者,2006 年至 2007 年间,69 名医生招募了 72 名患者。收集的数据包括治疗方法、医生和患者特征、结果,此外,在 2006 年至 2007 年的队列中,仅包括医生对他们通常提供的治疗方法变化的看法。

结果

使用抗生素的频率相似:最近的队列中为 79%,十年前为 77%(p = 0.63),口服抗生素治疗也相似(接受抗生素治疗的患者中 91%与 88%;p = 0.44)。最近的队列中更频繁地提供缓解症状的治疗。例如,解热药(54%比 34%;p = 0.001)、氧气(29%比 13%;p < 0.001)和阿片类药物(22%比 10%;p = 0.003)。这些差异不能用不同的病例组合来解释。一半的医生(49%)表示,与以前相比,他们通常更频繁地治疗以缓解症状。

结论

与十年前相比,荷兰患有痴呆症和肺炎的患者接受症状缓解治疗的频率更高,而使用抗生素的比率没有变化。需要在荷兰和其他地方进行进一步的研究,以检测这是否是一种普遍趋势。

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