• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Reply to 'Heterogeneity within AML with CEBPA mutations; only CEBPA double mutations, but not single CEBPA mutations are associated with favorable prognosis'.

作者信息

Hou H-A, Lin L-I, Chen C-Y, Tien H-F

出版信息

Br J Cancer. 2009 Aug 18;101(4):738-40. doi: 10.1038/sj.bjc.6605207. Epub 2009 Jul 21.

DOI:10.1038/sj.bjc.6605207
PMID:19623175
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2736811/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b83f/2736811/582469537556/6605207f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b83f/2736811/f86dd5d02632/6605207f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b83f/2736811/582469537556/6605207f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b83f/2736811/f86dd5d02632/6605207f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b83f/2736811/582469537556/6605207f2.jpg

相似文献

1
Reply to 'Heterogeneity within AML with CEBPA mutations; only CEBPA double mutations, but not single CEBPA mutations are associated with favorable prognosis'.对“伴有CEBPA突变的急性髓系白血病中的异质性：仅CEBPA双突变而非单CEBPA突变与良好预后相关”的回复
Br J Cancer. 2009 Aug 18;101(4):738-40. doi: 10.1038/sj.bjc.6605207. Epub 2009 Jul 21.
2
Heterogeneity within AML with CEBPA mutations; only CEBPA double mutations, but not single CEBPA mutations are associated with favourable prognosis.伴有CEBPA突变的急性髓系白血病（AML）存在异质性；只有CEBPA双突变而非CEBPA单突变与良好预后相关。
Br J Cancer. 2009 Apr 21;100(8):1343-6. doi: 10.1038/sj.bjc.6604977. Epub 2009 Mar 10.
3
CEBPA gene mutations in Egyptian acute myeloid leukemia patients: impact on prognosis.埃及急性髓系白血病患者中的CEBPA基因突变：对预后的影响。
Hematology. 2013 Mar;18(2):61-8. doi: 10.1179/1607845412Y.0000000032. Epub 2012 Sep 14.
4
Deficient CEBPA DNA binding function in normal karyotype AML patients is associated with favorable prognosis.核转录因子 CEBPA 基因结合功能缺陷的正常核型 AML 患者具有良好的预后。
Blood. 2011 May 5;117(18):4881-4. doi: 10.1182/blood-2010-11-320747. Epub 2011 Mar 9.
5
Prognostic implications of CEBPA mutations in pediatric acute myeloid leukemia: a report from the Japanese Pediatric Leukemia/Lymphoma Study Group.儿童急性髓系白血病中CEBPA突变的预后意义：来自日本儿童白血病/淋巴瘤研究组的报告
Blood Cancer J. 2014 Jul 11;4(7):e226. doi: 10.1038/bcj.2014.47.
6
[NPM1 and CEBPA mutations in pediatric cytogenetically normal acute myeloid leukemia].儿童细胞遗传学正常的急性髓系白血病中的NPM1和CEBPA突变
Zhonghua Er Ke Za Zhi. 2014 Apr;52(4):303-7.
7
Long-term follow-up of cytogenetically normal CEBPA-mutated AML.细胞遗传学正常的CEBPA突变型急性髓系白血病的长期随访
J Hematol Oncol. 2014 Sep 10;7:55. doi: 10.1186/s13045-014-0055-7.
8
Laboratory evaluation and prognostication among adults and children with CEBPA-mutant acute myeloid leukemia.CEBPA 突变型急性髓系白血病成人和儿童的实验室评估与预后判断。
Int J Lab Hematol. 2021 Jul;43 Suppl 1:86-95. doi: 10.1111/ijlh.13517.
9
Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome.双CEBPA突变而非单CEBPA突变定义了急性髓系白血病的一个亚组，该亚组具有独特的基因表达谱，且与良好预后唯一相关。
Blood. 2009 Mar 26;113(13):3088-91. doi: 10.1182/blood-2008-09-179895. Epub 2009 Jan 26.
10
Combined testing for CCAAT/enhancer-binding protein alpha (CEBPA) mutations and promoter methylation in acute myeloid leukemia demonstrates shared phenotypic features.急性髓系白血病中 CCAAT/增强子结合蛋白α（CEBPA）突变和启动子甲基化的联合检测显示出共同的表型特征。
Leuk Res. 2011 Feb;35(2):200-7. doi: 10.1016/j.leukres.2010.09.018. Epub 2010 Oct 20.

引用本文的文献

1
CEBPA mutations in acute myeloid leukemia: implications in risk stratification and treatment.CEBPA 基因突变在急性髓系白血病中的意义：对风险分层和治疗的影响。
Int J Hematol. 2024 Nov;120(5):541-547. doi: 10.1007/s12185-024-03773-5. Epub 2024 Apr 26.
2
Sporadic and Familial Acute Myeloid Leukemia with CEBPA Mutations.散发性和家族性伴有 CEBPA 突变的急性髓系白血病。
Curr Hematol Malig Rep. 2023 Oct;18(5):121-129. doi: 10.1007/s11899-023-00699-3. Epub 2023 Jun 1.
3
[Comparison of genetic mutations in myelodysplastic syndrome and acute myeloid leukemia].

本文引用的文献

1
Heterogeneity within AML with CEBPA mutations; only CEBPA double mutations, but not single CEBPA mutations are associated with favourable prognosis.伴有CEBPA突变的急性髓系白血病（AML）存在异质性；只有CEBPA双突变而非CEBPA单突变与良好预后相关。
Br J Cancer. 2009 Apr 21;100(8):1343-6. doi: 10.1038/sj.bjc.6604977. Epub 2009 Mar 10.
2
Characterization of acute myeloid leukemia with PTPN11 mutation: the mutation is closely associated with NPM1 mutation but inversely related to FLT3/ITD.伴有PTPN11突变的急性髓系白血病的特征：该突变与NPM1突变密切相关，但与FLT3/ITD呈负相关。
Leukemia. 2008 May;22(5):1075-8. doi: 10.1038/sj.leu.2405005. Epub 2007 Nov 1.
3
骨髓增生异常综合征与急性髓系白血病基因突变的比较
Zhonghua Xue Ye Xue Za Zhi. 2021 Feb 14;42(2):171-176. doi: 10.3760/cma.j.issn.0253-2727.2021.02.015.
4
Overexpression of SOX4 correlates with poor prognosis of acute myeloid leukemia and is leukemogenic in zebrafish.SOX4 的过表达与急性髓系白血病的不良预后相关，并在斑马鱼中具有致白血病性。
Blood Cancer J. 2017 Aug 25;7(8):e593. doi: 10.1038/bcj.2017.74.
5
Retinoic acid and arsenic trioxide in the treatment of acute promyelocytic leukemia: current perspectives.维甲酸与三氧化二砷治疗急性早幼粒细胞白血病：当前观点
Onco Targets Ther. 2017 Mar 14;10:1585-1601. doi: 10.2147/OTT.S100513. eCollection 2017.
6
Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel.成人急性髓系白血病的诊断与管理：2017年国际专家小组的欧洲白血病网络（ELN）建议
Blood. 2017 Jan 26;129(4):424-447. doi: 10.1182/blood-2016-08-733196. Epub 2016 Nov 28.
7
Clinical and prognostic implications of Roundabout 4 (robo4) in adult patients with acute myeloid leukemia.成人急性髓系白血病中Roundabout 4（robo4）的临床及预后意义
PLoS One. 2015 Mar 20;10(3):e0119831. doi: 10.1371/journal.pone.0119831. eCollection 2015.
8
The N-terminal CEBPA mutant in acute myeloid leukemia impairs CXCR4 expression.急性髓系白血病中的N端CEBPA突变体损害CXCR4表达。
Haematologica. 2014 Dec;99(12):1799-807. doi: 10.3324/haematol.2014.107821. Epub 2014 Sep 5.
9
Overexpression of wild-type or mutants forms of CEBPA alter normal human hematopoiesis.野生型或突变型 CEBPA 的过表达改变正常的人类造血。
Leukemia. 2012 Jul;26(7):1537-46. doi: 10.1038/leu.2012.38. Epub 2012 Feb 10.
10
Transcription factor mutations in myelodysplastic/myeloproliferative neoplasms.转录因子突变在骨髓增生异常/骨髓增殖性肿瘤中的作用。
Haematologica. 2010 Sep;95(9):1473-80. doi: 10.3324/haematol.2010.021808. Epub 2010 Apr 26.
FLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myeloid leukemia lacking FLT3 internal tandem duplications.
在缺乏FLT3内部串联重复的初发性细胞遗传学正常的急性髓系白血病年轻成人患者中，FLT3 D835/I836突变与无病生存期差及独特的基因表达特征相关。
Blood. 2008 Feb 1;111(3):1552-9. doi: 10.1182/blood-2007-08-107946. Epub 2007 Oct 16.
4
Characterization of CEBPA mutations in acute myeloid leukemia: most patients with CEBPA mutations have biallelic mutations and show a distinct immunophenotype of the leukemic cells.急性髓系白血病中CEBPA突变的特征：大多数CEBPA突变患者存在双等位基因突变，且白血病细胞呈现独特的免疫表型。
Clin Cancer Res. 2005 Feb 15;11(4):1372-9. doi: 10.1158/1078-0432.CCR-04-1816.
5
High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia.骨髓增生异常综合征及低原始细胞比例的伴有骨髓增生异常的髓系白血病中AML1/RUNX1基因体细胞突变的高发生率。
Blood. 2004 Mar 15;103(6):2316-24. doi: 10.1182/blood-2003-09-3074. Epub 2003 Nov 13.
6
CD56 antigenic expression in acute myeloid leukemia identifies patients with poor clinical prognosis.急性髓系白血病中CD56抗原表达可识别临床预后不良的患者。
Leukemia. 2001 Aug;15(8):1161-4. doi: 10.1038/sj.leu.2402174.
7
Screening for MLL tandem duplication in 387 unselected patients with AML identify a prognostically unfavorable subset of AML.对387例未经选择的急性髓系白血病（AML）患者进行MLL串联重复筛查，确定了AML中预后不良的一个亚组。
Leukemia. 2000 May;14(5):796-804. doi: 10.1038/sj.leu.2401773.