Tumarkin Ethan, Kumacheva Eugenia
Chem Soc Rev. 2009 Aug;38(8):2161-8. doi: 10.1039/b809915b. Epub 2009 May 14.
In this tutorial review we discuss recent advances in the application of microfluidics for the generation of microgels from synthetic and biological polymers. We summarize advantages and drawbacks of the current methods used in microfluidic synthesis and assembly of polymer microgels. Continuous microfluidic encapsulation of cells is discussed as an exemplary application of the microgels. The article is finalized with a perspective on future research in the field. The article will be of interest to chemists, cell biologists, pharmacologists, and medicinal chemists.
在本教程综述中，我们讨论了微流控技术在从合成聚合物和生物聚合物生成微凝胶方面应用的最新进展。我们总结了微流控合成和组装聚合物微凝胶中当前使用方法的优缺点。细胞的连续微流控封装作为微凝胶的一个典型应用进行了讨论。文章最后展望了该领域未来的研究方向。本文将对化学家、细胞生物学家、药理学家和药物化学家有吸引力。
