Hua Yongli, Huang Luqi, Chen Meilan, Xiao Peigen
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Zhongguo Zhong Yao Za Zhi. 2009 Apr;34(7):924-8.
The authors propose suggestions for definition of classification position, classification standard, nomenclature and naming methods of chemotype on discussing the significance of chemotype of medicinal plants. This classification of chemotype should be established in infraspecific categories of "forma". Chemotype identification mainly has two aspects. One is that the main constituents are distinct or one or two components are half or more than half of the total chemical content. The main constituents come from the same biosynthetic pathway and have some genetic stability. The other is the chemical variation is genetic. The chemotype of medicinal plants study on the classification has important theoretical and practical value for quality assessment, resource development and the genuine medicinal research. It also can ensure the safe and effective of clinical medicine.
作者在论述药用植物化学型的意义时，对化学型的分类地位、分类标准、命名及命名方法提出了建议。这种化学型分类应建立在“变型”的种下等级中。化学型鉴定主要有两个方面。一是主要成分不同，或者一两种成分占总化学含量的一半或一半以上。主要成分来自相同的生物合成途径，具有一定的遗传稳定性。另一个是化学变异具有遗传性。药用植物化学型分类研究对于质量评价、资源开发和道地药材研究具有重要的理论和实践价值。它还能确保临床用药的安全有效。
