Palma Aniello, Tasior Mariusz, Frimannsson Daniel O, Vu Thanh Truc, Méallet-Renault Rachel, O'Shea Donal F
Centre for Synthesis and Chemical Biology, School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland.
Org Lett. 2009 Aug 20;11(16):3638-41. doi: 10.1021/ol901413u.
The facile synthesis and photophysical characterization of new on-bead fluorophores and fluorescent sensors are described. The unique covalent immobilization strategy results in highly fluorescent beads with sharp emission profiles between 650 and 800 nm. Illustrative examples include imaging in an aqueous cellular environment and adaptation to include off/on sensing functionality, proven by a prototypical detection of gaseous HCl.
本文描述了新型珠上荧光团和荧光传感器的简便合成方法及光物理特性。独特的共价固定策略可产生发射峰在650至800纳米之间、具有高荧光性的珠子。示例包括在水性细胞环境中的成像以及具备开/关传感功能的适应性应用，气态HCl的原型检测证明了这一点。
