Huang Lehao, Zhang Xunbin, Zhang Yuhong
Department of Chemistry, Zhejiang University, Hangzhou 310027, People's Republic of China.
Org Lett. 2009 Aug 20;11(16):3730-3. doi: 10.1021/ol901347t.
A wide range of silyl enol ethers undergo the reactions with N,N-dimethylanilines in the presence of transition metal catalysts under mild conditions to give beta-arylamino ketones. In the cases of silyl enol ethers derived from unsymmetrical ketones, regiospecific addition of carbonyl compounds was obtained at the olefinic position of silyl enol ether.
在温和条件下，多种甲硅烷基烯醇醚在过渡金属催化剂存在下与N，N - 二甲基苯胺发生反应，生成β-芳氨基酮。对于由不对称酮衍生的甲硅烷基烯醇醚，在甲硅烷基烯醇醚的烯属位置实现了羰基化合物的区域选择性加成。
