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哥伦比亚波哥大两个眼科中心葡萄膜炎的临床模式

Clinical patterns of uveitis in two ophthalmology centres in Bogota, Colombia.

作者信息

de-la-Torre Alejandra, López-Castillo Christian Adrián, Rueda Juan C, Mantilla Rubén Darío, Gómez-Marín Jorge Enrique, Anaya Juan-Manuel

机构信息

Grupo de Estudio en Parasitología Molecular (GEPAMOL), Universidad del Quindío, Armenia, Colombia.

出版信息

Clin Exp Ophthalmol. 2009 Jul;37(5):458-66. doi: 10.1111/j.1442-9071.2009.02082.x.

Abstract

PURPOSE

To describe the distribution pattern and the clinical features of uveitis in two ophthalmology referral centres in Colombia.

METHODS

This was a retrospective study in which clinical records of patients attending the centres between 1996 and 2006 were systematically reviewed. Data were analysed and compared with previous reports.

RESULTS

Uveitis was found in 693 patients: 335 men (48.3%) and 358 women (51.7%). The mean age for the first presentation was 31.7 +/- 18.3 years. Unilateral (73.4%), acute (68.3%), posterior (35.9%) and non-granulomatous (90.6%) were the most common types of uveitis found in the sample. Toxoplasmosis was the most frequent cause in this study followed in order by idiopathic and toxocariasis. Vogt-Koyanagi-Harada, Behçet's disease, sarcoidosis and white dot syndromes were less common. Some causes such as systemic lupus erythematosus and tuberculosis were extremely rare. Presumed ocular histoplasmosis, onchocerciasis and Lyme disease were absent.

CONCLUSIONS

The results of this study provide the first report of clinical patterns for uveitis in Colombia. This study will enhance awareness of uveitis, and data should assist in the development of public health policies in our population for the improvement of patient outcomes.

摘要

目的

描述哥伦比亚两个眼科转诊中心葡萄膜炎的分布模式和临床特征。

方法

这是一项回顾性研究,系统回顾了1996年至2006年间在这些中心就诊患者的临床记录。对数据进行分析并与先前报告进行比较。

结果

共发现693例葡萄膜炎患者,其中男性335例(48.3%),女性358例(51.7%)。首次发病的平均年龄为31.7±18.3岁。样本中最常见的葡萄膜炎类型为单侧(73.4%)、急性(68.3%)、后葡萄膜炎(35.9%)和非肉芽肿性(90.6%)。弓形虫病是本研究中最常见的病因,其次是特发性和弓蛔虫病。伏格特-小柳-原田病、白塞病、结节病和白点综合征较少见。系统性红斑狼疮和结核病等一些病因极为罕见。未发现推测性眼组织胞浆菌病、盘尾丝虫病和莱姆病。

结论

本研究结果首次报告了哥伦比亚葡萄膜炎的临床模式。本研究将提高对葡萄膜炎的认识,相关数据应有助于制定我国的公共卫生政策,以改善患者预后。

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