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Acute promyelocytic leukemia harboring a STAT5B-RARA fusion gene and a G596V missense mutation in the STAT5B SH2 domain of the STAT5B-RARA.

作者信息

Iwanaga Eisaku, Nakamura Miki, Nanri Tomoko, Kawakita Toshiro, Horikawa Kentaro, Mitsuya Hiroaki, Asou Norio

出版信息

Eur J Haematol. 2009 Nov;83(5):499-501. doi: 10.1111/j.1600-0609.2009.01324.x. Epub 2009 Jul 18.

DOI:10.1111/j.1600-0609.2009.01324.x
PMID:19624718
Abstract
摘要

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Acute promyelocytic leukemia harboring a STAT5B-RARA fusion gene and a G596V missense mutation in the STAT5B SH2 domain of the STAT5B-RARA.急性早幼粒细胞白血病,其STAT5B-RARA中存在STAT5B-RARA融合基因以及STAT5B SH2结构域中的G596V错义突变。
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[DNA sequence analysis of a novel variate type of PML/RAR alpha fusion gene transcript].[一种新型PML/RARα融合基因转录变体类型的DNA序列分析]
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Variant acute promyelocytic leukemia translocation (15;17) originating from two subsequent balanced translocations involving the same chromosomes 15 and 17 while preserving the PML/RARA fusion.变异型急性早幼粒细胞白血病15;17易位,起源于涉及相同15号和17号染色体的两个连续平衡易位,同时保留PML/RARA融合基因。
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Clinical characteristics of acute promyelocytic leukemia with the STAT5B-RARA fusion gene.具有STAT5B-RARA融合基因的急性早幼粒细胞白血病的临床特征
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