Hemnes A R, Forfia P R, Champion H C
Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University, Nashville, TN, USA.
Int J Clin Pract Suppl. 2009 Sep(162):4-19. doi: 10.1111/j.1742-1241.2009.02110.x.
Understanding the haemodynamical profile of the right ventricle and pulmonary circulation is critical to not only the initial evaluation of, but also the continued management of pulmonary hypertension. Despite advances in non-invasive imaging techniques, right heart catheterisation (RHC) remains the gold standard for diagnosis of pulmonary hypertension and its various causes. Even so, integration of invasive haemodynamical data with the echo-Doppler exam provides the most comprehensive assessment of the pathophysiology of pulmonary hypertension in the individual patient. Here, we review technical aspects of basic RHC as well as specialised procedures including exercise and fluid challenge in the evaluation of pulmonary hypertension. Interpretation of data in the context of pulmonary vascular disease is discussed. Echocardiographical assessment of the right ventricular structure and function in pulmonary vascular disease are discussed along with the integration of haemodynamical and echocardiographical data in the clinical context.
了解右心室和肺循环的血流动力学特征不仅对肺动脉高压的初始评估至关重要,而且对其持续管理也至关重要。尽管无创成像技术取得了进展,但右心导管检查(RHC)仍然是诊断肺动脉高压及其各种病因的金标准。即便如此,将有创血流动力学数据与超声多普勒检查相结合,可为个体患者的肺动脉高压病理生理学提供最全面的评估。在此,我们回顾基本RHC的技术方面以及包括运动和液体激发试验在内的特殊程序在肺动脉高压评估中的应用。还将讨论在肺血管疾病背景下的数据解读。同时讨论肺血管疾病中右心室结构和功能的超声心动图评估,以及血流动力学和超声心动图数据在临床背景下的整合。