Kabigting Filamer D, Kempiak Stephan J, Alexandrescu Doru T, Yu Benajmin D
Department of Dermatology, University of California at San Diego, San Diego, California, USA.
Dermatol Online J. 2009 May 15;15(5):9.
Sea urchin injuries have been associated with a variety of cutaneous lesions, ranging from acute, transient reactions, to more chronic inflammatory conditions that result in the formation of granulomas. Although diverse species of sea urchins have been reported to produce chronic cutaneous granulomas, the two most prevalent organisms found on the US West Coast, purple and red sea urchins (Strongylocentrotus purpuratus and Strongylocentrotus franciscanus), have not yet been reported to induce persistent granulomatosis in humans. We describe one case of a 35-year-old marine biologist with chronic cutaneous lesions produced after repeated exposures. The lesions were similar to the ones produced by other urchin species, consisting of small, firm, erythematous nodules on his palms, dorsum of the hands, elbows, and knees. Increased awareness of this condition, including its association with the two prevalent organisms on the West Coast, should lead to a more rapid diagnosis for those affected. This article reviews the types of injuries, clinical cutaneoous lesions, histopathological features, and pathogenesis of the chronic inflammatory process induced by sea urchins.
海胆刺伤与多种皮肤损伤有关，从急性短暂反应到导致肉芽肿形成的更慢性炎症状态不等。尽管已报道多种海胆会引发慢性皮肤肉芽肿，但在美国西海岸发现的两种最常见的海胆，紫海胆和红海胆（紫球海胆和加州红海胆），尚未有报道称会在人类中诱发持续性肉芽肿病。我们描述了一例35岁海洋生物学家的病例，其在反复接触后出现了慢性皮肤损伤。这些损伤与其他海胆种类造成的损伤相似，表现为他手掌、手背、肘部和膝盖上的小而硬的红斑结节。提高对这种疾病的认识，包括其与西海岸两种常见生物的关联，应该会使受影响的人得到更快的诊断。本文综述了海胆所致损伤的类型、临床皮肤损伤、组织病理学特征以及慢性炎症过程的发病机制。
