Department of Cardiology, Mayo Clinic, Rochester, Minnesota 55905, USA.
Angiology. 2009;60(6):714-8. doi: 10.1177/0003319709335512. Epub 2009 Jul 21.
To describe the outcomes of treating patients with angioplasty who are older than 40 years with symptomatic/labile/refractory hypertension (HTN).
Between 1999 and 2005, 28 patients underwent angioplasty for renal fibromuscular dysplasia (FMD). Patients were excluded if they had concomitant atherosclerotic renal artery stenosis (n = 4) or less than 1 month follow-up (n = 8).
The study group included 16 Caucasians (21 procedures; mean age 65.5 +/- 10.8 years; females = 88%). The cardiovascular risk factors include HTN (n = 13), smoking (n = 1), diabetes (n = 2), dyslipidemia (n = 8). The HTN was characterized as refractory (n = 15, 12 were symptomatic) and new-onset in 1 patient. The technical success rate was 100%. Over a median period of 12.8 months (range: 1.0-85.8), 18 (95%) procedures ''failed,'' of which 8 (42%) within 1 month and the rest in 1 year.
Angioplasty in symptomatic renal FMD in patients >40 years is associated with poor outcomes possibly due to early restenosis.
描述治疗年龄大于 40 岁且伴有症状性/波动性/难治性高血压（HTN）的血管成形术患者的治疗结果。
1999 年至 2005 年，28 例因纤维肌性发育不良（FMD）而行血管成形术的患者纳入研究。如果患者合并有粥样硬化性肾动脉狭窄（n=4）或随访时间少于 1 个月（n=8），则将其排除在外。
研究组包括 16 名高加索人（21 例手术；平均年龄 65.5+/-10.8 岁；女性 88%）。心血管危险因素包括 HTN（n=13）、吸烟（n=1）、糖尿病（n=2）、血脂异常（n=8）。HTN 表现为难治性（n=15，其中 12 例有症状）和 1 例新发。技术成功率为 100%。在中位数为 12.8 个月（范围：1.0-85.8）的随访期间，18（95%）例手术“失败”，其中 8（42%）例在 1 个月内失败，其余在 1 年内失败。
年龄大于 40 岁且伴有症状性肾 FMD 的患者进行血管成形术，其治疗结果较差，可能与早期再狭窄有关。
