使用X因子显色测定法来接受或拒绝华法林治疗患者的国际标准化比值（INR）结果。
Use of chromogenic assay of factor X to accept or reject INR results in Warfarin treated patients.
作者信息
Sanfelippo Michael J, Zinsmaster Wendy, Scherr Doris L, Shaw Gene R
机构信息
Coagulation Services, Marshfield Labs, Marshfield Clinic, 1000 North Oak Avenue, Marshfield, WI 54449, USA.
出版信息
Clin Med Res. 2009 Sep;7(3):103-5. doi: 10.3121/cmr.2009.836. Epub 2009 Jul 22.
A warfarin treated patient unexpectedly presented with an elevated international normalized ratio (INR). Repeat testing in two laboratories gave conflicting results. The chromogenic assay of factor X was used to determine the correct INR result. The patient had laboratory results consistent with a dysfibrinogenemia, which prevented detection of the endpoint with a photo-optical detection system. The chromogenic assay of factor X is recommended for monitoring patients on warfarin when the INR cannot be accurately determined due to interference with the fibrin endpoint in the INR.
一名接受华法林治疗的患者意外出现国际标准化比值（INR）升高。在两个实验室重复检测得到了相互矛盾的结果。采用X因子显色测定法来确定正确的INR结果。该患者的实验室检查结果符合异常纤维蛋白原血症，这使得用光光学检测系统无法检测到终点。当因INR中纤维蛋白终点受到干扰而无法准确测定INR时，推荐采用X因子显色测定法来监测接受华法林治疗的患者。
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