Kamel Y M, Jefferson P, Ball D R
Dumfries and Galloway Royal Infirmary, Dumfries, UK.
Emerg Med J. 2009 Aug;26(8):609-10. doi: 10.1136/emj.2008.063776.
ILCOR recommend the use of therapeutic hypothermia (32-34 degrees C) for 12-24 h in unconscious adult patients with spontaneous circulation after cardiac arrest with a VF rhythm. Among various methods of inducing hypothermia, the rapid infusion of ice-cold intravenous fluid has been used.
To investigate the time required to cool intravenous fluids in a domestic refrigerator and freezer, bags of compound sodium lactate were placed on the upper shelf of a refrigerator. Continuous temperature measurement was performed for 2 h for 10 500 ml and 10 1000 ml bags. The procedure was then repeated in the freezer.
The mean time for 500 ml bags to cool to 4 degrees C or below was 90 minutes or more in a refrigerator and 60-90 minutes in the freezer. 1000 ml bags are cooled to 4 degrees C or below within 120 minutes in the freezer, but it takes longer in a refrigerator.
As induced hypothermia should be started as soon as possible in eligible patients, crystalloids should be stored in a refrigerator.
国际复苏联络委员会（ILCOR）建议，对于心脏骤停后恢复自主循环且为室颤节律的昏迷成年患者，采用治疗性低温（32 - 34摄氏度）持续12 - 24小时。在各种诱导低温的方法中，已采用快速输注冰冷静脉输液的方式。
为研究在家庭冰箱和冰柜中冷却静脉输液所需的时间，将复方乳酸钠袋放置在冰箱的上层搁板上。对10袋500毫升和10袋1000毫升的袋子持续进行2小时的温度测量。然后在冰柜中重复该过程。
在冰箱中，500毫升袋子冷却至4摄氏度或更低的平均时间为90分钟或更长，在冰柜中为60 - 90分钟。1000毫升袋子在冰柜中120分钟内可冷却至4摄氏度或更低，但在冰箱中所需时间更长。
由于符合条件的患者应尽快开始诱导低温，晶体液应储存在冰箱中。
