Drug dosing in patients with impaired renal function.
作者信息
Brater D C
机构信息
Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
出版信息
Clin Pharmacol Ther. 2009 Nov;86(5):483-9. doi: 10.1038/clpt.2009.135. Epub 2009 Jul 22.
PMID:19626002
Abstract
Renal function can affect disposition and response to drugs in a variety of ways. This review discusses the principles underlying such responses, with particular emphasis on how changes in disposition parameters affect dosing decisions.
摘要
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