泌尿系统畸形胎儿的肺容积：二维超声、三维超声与磁共振成像的比较

Fetal lung volume in fetuses with urinary tract malformations: comparison by 2D-, 3D-sonography and magnetic resonance imaging.

作者信息

Araujo Júnior Edward, De Oliveira Patrícia Soares, Nardozza Luciano Marcondes Machado, Simioni Christiane, Rolo Liliam Cristine, Goldman Susan Menasce, Szejnfeld Jacob, Moron Antonio Fernandes

机构信息

Obstetrics Department of São Paulo Federal University (UNIFESP), São Paulo, São Paulo, Brazil.

出版信息

J Matern Fetal Neonatal Med. 2010 Jan;23(1):60-8. doi: 10.3109/14767050903121415.

DOI:10.3109/14767050903121415

PMID:19626568

Abstract

OBJECTIVE

To evaluate the concordance between two-dimensional ultrasonography (2DUS), three-dimensional ultrasonography (3DUS) and magnetic resonance imaging (MRI) in the assessment of lung volume in fetuses with urinary tract malformations (UTM).

METHODS

This was a cross-sectional study involving 12 pregnancies between 19 and 34 weeks, with various fetal UTM. Pulmonary volume was obtained by 2DUS using the following equation: total lung volume = [right lung antero-posterior diameter (X) x transverse diameter (Y) x cranial-caudal diameter x 0.152 + left lung (X1) x (Y1) x (Z1) x 0.167]. Pulmonary volume by 3DUS was obtained using the virtual organ computer-aided analysis (VOCAL) method with a 30 degrees (VOL30), 18 degrees (VOL18) and 12 degrees (VOL12) rotation. A fast sequence of transverse lung section was also obtained by MRI. The intraclass correlation coefficient was used to evaluate the correlation between the three methods. The paired student t-test was used to compare the means.

RESULTS

There was a strong correlation between the three methods, and the highest correlations were between MRI and VOL18 for the right (ICC = 0.913) and left (ICC = 0.947) lungs. A strong correlation was also found between the lung volumes obtained through MRI and VOL12 as well as VOL18 (p = 0.544 and 0.286, respectively). However, for the left lung there was only a correlation between MRI and VOL12 (p = 0.49).

CONCLUSIONS

There is a good concordance between 3DUS (VOL12) and MRI in the evaluation of lung volume in fetuses with UTM.

摘要

目的

评估二维超声检查（2DUS）、三维超声检查（3DUS）和磁共振成像（MRI）在评估泌尿系统畸形（UTM）胎儿肺容积方面的一致性。

方法

这是一项横断面研究，纳入了12例妊娠19至34周、患有各种胎儿UTM的孕妇。通过2DUS使用以下公式获得肺容积：总肺容积 = [右肺前后径（X）×横径（Y）×头尾径×0.152 + 左肺（X1）×（Y1）×（Z1）×0.167]。通过虚拟器官计算机辅助分析（VOCAL）方法，以30度（VOL30）、18度（VOL18）和12度（VOL12）旋转获得3DUS的肺容积。MRI也获得了快速的横向肺切片序列。组内相关系数用于评估三种方法之间的相关性。配对学生t检验用于比较均值。

结果

三种方法之间存在强相关性，右肺和左肺的MRI与VOL18之间的相关性最高（右肺ICC = 0.913，左肺ICC = 0.947）。通过MRI获得的肺容积与VOL12以及VOL18之间也发现了强相关性（分别为p = 0.544和0.286）。然而，对于左肺，仅在MRI与VOL12之间存在相关性（p = 0.49）。