胎儿肺容积：二维和三维超声检查对正常胎儿的比较

Fetal lung volume: comparison by 2D- and 3D-sonography in normal fetuses.

作者信息

Britto Ingrid Schwach Werneck, de Silva Bussamra Luiz Cláudio, Araujo Júnior Edward, Tedesco Giselle Darahem, Nardozza Luciano Marcondes Machado, Moron Antonio Fernandes, Aoki Tsutomu

机构信息

Department of Gynecology and Obstetrics, Medical Science College of Santa Casa of São Paulo (FCMSCSP), São Paulo, SP, Brazil.

出版信息

Arch Gynecol Obstet. 2009 Sep;280(3):363-8. doi: 10.1007/s00404-008-0908-9. Epub 2009 Jan 9.

DOI:10.1007/s00404-008-0908-9

PMID:19132381

Abstract

PURPOSE

To compare two-dimensional ultrasonography (2D US) and three-dimensional ultrasonography (3D US) in the assessment of normal fetal lung volume.

METHODS

A cross-sectional study was performed involving 50 normal pregnancies at 24-32 weeks' gestation. The following equations were used for lung volume calculation by 2D US: Eq(2D1) = 4.24 + {1.53 x [(area of base of both lungs) x 1/3 (height of right lung)]} and Eq(2D2) = [anteroposterior diameter (X) x transverse diameter (Y) x cranial-caudal diameter (Z) of the right lung x 0.152 + (X') x (Y') x (Z') of the left lung x 0.167]. For 3D US, the virtual organ computer-aided analysis (VOCAL) method was used with a 30 degrees rotation angle and the total lung volume (V3D) was obtained by summing the volumes of each lung. Regression models (R (2)) were devised to assess lung volume evolution over the course of the pregnancy. Pearson's correlation coefficient (r) was used to assess correlation among the techniques, while Friedman's test was used for means comparisons.

RESULTS

Strong correlation was observed among the three techniques [V3D vs. Eq(2D2) r = 0.856; V3D vs. Eq(2D1) r = 0.838 and Eq(2D2) vs. Eq(2D1) r = 0.964; all with P < 0.001]. Mean lung volumes were 37.05 +/- 9.67, 29.79 +/- 8.79 and 12.67 +/- 4.12 ml for V3D, Eq(2D1) and Eq(2D2), respectively (P < 0.001).

CONCLUSIONS

Strong correlation and significant difference was observed among the three techniques of fetal lung volume assessment in normal fetuses.

摘要

目的

比较二维超声（2D US）和三维超声（3D US）在评估正常胎儿肺容积方面的差异。

方法

进行了一项横断面研究，纳入了50例孕24 - 32周的正常妊娠。通过二维超声使用以下公式计算肺容积：公式（2D1）= 4.24 + {1.53×[双侧肺底部面积×1/3（右肺高度）]}，公式（2D2）= [右肺前后径（X）×横径（Y）×头尾径（Z）×0.152 + 左肺的（X'）×（Y'）×（Z'）×0.167]。对于三维超声，使用虚拟器官计算机辅助分析（VOCAL）方法，旋转角度为30度，通过将每个肺的容积相加得到总肺容积（V3D）。设计回归模型（R²）以评估孕期肺容积的变化。采用Pearson相关系数（r）评估技术之间的相关性，而Friedman检验用于均值比较。

结果

三种技术之间观察到强相关性[V3D与公式（2D2），r = 0.856；V3D与公式（2D1），r = 0.838；公式（2D2）与公式（2D1），r = 0.964；均P < 0.001]。V3D、公式（2D1）和公式（2D2）的平均肺容积分别为37.05±9.67、29.79±8.79和12.67±4.12 ml（P < 0.001）。