Covarsi A, Rodriguez A M, Marigliano N, Novillo R
Department of Medicine, General Hospital of INSALUD, Cáceres, Spain.
Am J Nephrol. 1991;11(3):224-8. doi: 10.1159/000168307.
Acquired renal cystic disease is an entity which is characterized by the progressive substitution of the atrophic renal parenchyma by multiple cysts in patients with renal insufficiency. Its main complications are hemorrhage and tumorous degeneration. The case discussed is a 57-year-old patient with terminal renal insufficiency secondary to interstitial nephropathy, who, following 6 years of treatment with hemodialysis and renal transplantation, developed a state of persistent hematuria requiring nephrectomy of the left kidney. Histological study revealed multiple cysts of monostratified epithelium with intracavitary projections, multiform adenomas and multifocal malignant tumorous polymorphism. The patient died in a state of progressive cachexia with pleural and hepatic metastasis.
获得性肾囊肿病是一种以肾功能不全患者萎缩的肾实质逐渐被多个囊肿替代为特征的疾病。其主要并发症是出血和肿瘤变性。所讨论的病例是一名57岁因间质性肾病导致终末期肾功能不全的患者，在接受6年血液透析和肾移植治疗后，出现持续血尿状态，需要切除左肾。组织学研究显示有单层上皮的多个囊肿，伴有腔内突起、多形性腺瘤和多灶性恶性肿瘤多形性。患者死于进行性恶病质状态，伴有胸膜和肝转移。
