Delvat E, Gordin D M, Gloriant T, Duval J L, Nagel M D
INSA Rennes, UMR CNRS 6226 Sciences Chimiques de Rennes/Chimie-Métallurgie, 20 avenue des Buttes de Coësmes, F-35043 Rennes cedex, France.
J Mech Behav Biomed Mater. 2008 Oct;1(4):345-51. doi: 10.1016/j.jmbbm.2008.01.006. Epub 2008 Feb 7.
We have synthesized titanium-based alloys containing molybdenum and tantalum elements by powder metallurgy. The microstructure, the residual porosity and the mechanical properties of the sintered Ti-Mo and Ti-Ta-Mo alloys were investigated by using optical and electronic microscopy, X-ray diffraction, microhardness and compression tests. The cytocompatibility of the different alloys was evaluated by the assessment of bone cell density, migration and adhesion after 14 days incubation. All the alloys present a high ductility and an excellent cytocompatibility, which make these materials useful for medical implants.
我们通过粉末冶金法合成了含钼和钽元素的钛基合金。利用光学显微镜、电子显微镜、X射线衍射、显微硬度和压缩试验研究了烧结Ti-Mo合金和Ti-Ta-Mo合金的微观结构、残余孔隙率及力学性能。通过评估14天培养后骨细胞密度、迁移和黏附情况来评价不同合金的细胞相容性。所有合金均具有高延展性和优异的细胞相容性，这使得这些材料可用于医用植入物。
