School of Primary Health Care, Monash University, Melbourne, Australia.
Mol Cell Endocrinol. 2010 Mar 25;316(2):104-8. doi: 10.1016/j.mce.2009.07.008. Epub 2009 Jul 21.
The prevalence of obesity has progressively increased globally over the last 30 years. The determinants of this pandemic are many, poorly defined and priorities debated. While public health measures to prevent obesity have largely failed we are presented with a growing burden of disease and disability. Cardiovascular disease, type-2 diabetes, obesity related cancers, osteoarthritis and psychological disturbance generate much of the morbidity and years of life lost associated with increasing levels of obesity. Obesity has a clearly measurable impact on physical and mental health, health related quality of life, and generates considerable direct and indirect costs. The evolving obesity pandemic is exacting a considerable toll on those affected, the treating health services, and on our communities. Weight loss appears to be the most effective therapy for obesity and obesity related comorbidity. As health care researchers and providers we are likely to play a peripheral role in the prevention of obesity, but a central role in effectively treating those afflicted by the obesity pandemic.
在过去的 30 年中,肥胖症在全球范围内的患病率呈逐渐上升趋势。导致肥胖症的因素有很多,且这些因素尚未明确界定,优先事项也存在争议。尽管预防肥胖的公共卫生措施在很大程度上失败了,但我们正面临着越来越多的疾病和残疾负担。心血管疾病、2 型糖尿病、肥胖相关癌症、骨关节炎和心理障碍等疾病导致了与肥胖程度增加相关的大部分发病率和丧失的生命年。肥胖症对身心健康、健康相关生活质量有明显的可衡量的影响,并产生了相当大的直接和间接成本。不断演变的肥胖症大流行给受影响的人群、治疗保健服务以及我们的社区带来了巨大的损失。减肥似乎是治疗肥胖症和肥胖相关并发症最有效的方法。作为医疗保健研究人员和提供者,我们可能在预防肥胖症方面发挥次要作用,但在有效治疗肥胖症大流行患者方面发挥核心作用。