• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Cross-talk between transcription factors AhR and Nrf2: lessons for cancer chemoprevention from dioxin.

作者信息

Hayes John D, Dinkova-Kostova Albena T, McMahon Michael

机构信息

Biomedical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK.

出版信息

Toxicol Sci. 2009 Oct;111(2):199-201. doi: 10.1093/toxsci/kfp168. Epub 2009 Jul 23.

DOI:10.1093/toxsci/kfp168
PMID:19628587
Abstract
摘要

相似文献

1
Cross-talk between transcription factors AhR and Nrf2: lessons for cancer chemoprevention from dioxin.转录因子芳烃受体(AhR)与核因子E2相关因子2(Nrf2)之间的相互作用:二噁英对癌症化学预防的启示
Toxicol Sci. 2009 Oct;111(2):199-201. doi: 10.1093/toxsci/kfp168. Epub 2009 Jul 23.
2
Coordinate regulation of Phase I and II xenobiotic metabolisms by the Ah receptor and Nrf2.芳烃受体(Ah受体)和核因子E2相关因子2(Nrf2)对异生物代谢I相和II相的协同调节
Biochem Pharmacol. 2007 Jun 15;73(12):1853-62. doi: 10.1016/j.bcp.2007.01.009. Epub 2007 Jan 7.
3
Carcinogenic risks of dioxin: mechanistic considerations.二噁英的致癌风险:机制探讨
Regul Toxicol Pharmacol. 2005 Oct;43(1):19-34. doi: 10.1016/j.yrtph.2005.05.008.
4
Activation of coupled Ah receptor and Nrf2 gene batteries by dietary phytochemicals in relation to chemoprevention.膳食植物化学物质对化学预防相关的Ah受体和Nrf2基因簇的激活作用。
Biochem Pharmacol. 2006 Sep 28;72(7):795-805. doi: 10.1016/j.bcp.2006.04.017. Epub 2006 Apr 29.
5
The Aryl Hydrocarbon Receptor and Its Crosstalk: A Chemopreventive Target of Naturally Occurring and Modified Phytochemicals.芳基烃受体及其串扰:天然存在和修饰植物化学物质的化学预防靶点。
Molecules. 2024 Sep 10;29(18):4283. doi: 10.3390/molecules29184283.
6
The mammalian aryl hydrocarbon (Ah) receptor: from mediator of dioxin toxicity toward physiological functions in skin and liver.哺乳动物芳基烃(Ah)受体:从二恶英毒性的介质到皮肤和肝脏中的生理功能。
Biol Chem. 2009 Dec;390(12):1225-35. doi: 10.1515/BC.2009.138.
7
Receptor-mediated carcinogenesis: the role of biological effect modeling for risk assessment of dioxin and tamoxifen.受体介导的致癌作用:生物效应模型在二噁英和他莫昔芬风险评估中的作用。
Prog Clin Biol Res. 1996;394:113-29.
8
Expression of aryl hydrocarbon receptor, inflammatory cytokines, and incidence of rheumatoid arthritis in Vietnamese dioxin-exposed people.芳香烃受体、炎症细胞因子的表达与越南二恶英暴露人群类风湿关节炎的发病情况。
J Immunotoxicol. 2017 Dec;14(1):196-203. doi: 10.1080/1547691X.2017.1377323.
9
Molecular interactions of the aryl hydrocarbon receptor and its biological and toxicological relevance for reproduction.芳烃受体的分子相互作用及其对生殖的生物学和毒理学意义。
Reproduction. 2005 Apr;129(4):379-89. doi: 10.1530/rep.1.00294.
10
The AhR-Nrf2 pathway in keratinocytes: on the road to chemoprevention?角质细胞中的 AhR-Nrf2 通路:走向化学预防?
J Invest Dermatol. 2012 Jan;132(1):7-9. doi: 10.1038/jid.2011.359.

引用本文的文献

1
Breast Cancer Cytochromes P450: Chemopreventive and/or Therapeutic Targets for Naturally Occurring Phytochemicals.乳腺癌细胞色素P450:天然植物化学物质的化学预防和/或治疗靶点
Molecules. 2025 Jul 23;30(15):3079. doi: 10.3390/molecules30153079.
2
Chemical Inhibition of NRF2 Transcriptional Activity Influences Colon Function and Oestrogen Receptor Expression in Mice at Different Ages.NRF2转录活性的化学抑制对不同年龄小鼠的结肠功能和雌激素受体表达有影响。
Int J Mol Sci. 2024 Dec 20;25(24):13647. doi: 10.3390/ijms252413647.
3
Differential Modulatory Effects of Methylmercury (MeHg) on Ahr-regulated Genes in Extrahepatic Tissues of C57BL/6 Mice.
甲基汞(MeHg)对 C57BL/6 小鼠肝外组织中 Ahr 调控基因的差异调节作用。
Biol Trace Elem Res. 2024 Nov;202(11):5071-5080. doi: 10.1007/s12011-023-04050-y. Epub 2024 Jan 10.
4
Development of skin diseases following systemic exposure: example of dioxins.全身暴露后皮肤病的发生:以二恶英为例。
Front Toxicol. 2023 Aug 28;5:1243192. doi: 10.3389/ftox.2023.1243192. eCollection 2023.
5
Jdp2 is a spatiotemporal transcriptional activator of the AhR via the Nrf2 gene battery.Jdp2是通过Nrf2基因簇对芳烃受体进行时空转录激活的因子。
Inflamm Regen. 2023 Aug 18;43(1):42. doi: 10.1186/s41232-023-00290-6.
6
Health Benefits of Coffee Consumption for Cancer and Other Diseases and Mechanisms of Action.咖啡消费对癌症和其他疾病的健康益处及其作用机制。
Int J Mol Sci. 2023 Jan 31;24(3):2706. doi: 10.3390/ijms24032706.
7
Cancer risk in Vietnam war veterans from the Korean Vietnam war veterans' health study cohort.来自朝鲜-越南战争退伍军人健康研究队列的越南战争退伍军人的癌症风险。
Front Oncol. 2023 Jan 25;13:1048820. doi: 10.3389/fonc.2023.1048820. eCollection 2023.
8
Transcriptional Regulation of by Aryl Hydrocarbon Receptor: Effect on Math1 Progenitor Cells in Mouse Small Intestine.芳香烃受体对 的转录调控:对小鼠小肠 Math1 祖细胞的影响。
Mol Cell Biol. 2023 Jan;43(1):43-63. doi: 10.1080/10985549.2022.2160610. Epub 2023 Jan 26.
9
GSTM2 is a key molecular determinant of resistance to SG-ARIs.GSTM2 是对 SG-ARIs 产生耐药性的关键分子决定因素。
Oncogene. 2022 Sep;41(40):4498-4511. doi: 10.1038/s41388-022-02444-1. Epub 2022 Aug 29.
10
The Role of Organosulfur Compounds as Nrf2 Activators and Their Antioxidant Effects.有机硫化合物作为Nrf2激活剂的作用及其抗氧化作用。
Antioxidants (Basel). 2022 Jun 26;11(7):1255. doi: 10.3390/antiox11071255.