Lempert T
Neurologische Abteilung, Schlosspark-Klinik, 14059 Berlin.
Nervenarzt. 2009 Aug;80(8):895-9. doi: 10.1007/s00115-009-2737-x.
Vestibular migraine (VM) presents with attacks of spontaneous or positional vertigo lasting seconds to days. Headaches are often absent during acute attacks, but other symptoms of migraine, such as photophobia or auras may be present. Like migraine headaches VM triggers may include stress, sleep deprivation and hormonal changes. During acute attacks there may be central spontaneous or positional nystagmus and, less commonly, unilateral vestibular hypofunction. In the symptom-free interval vestibular testing shows mostly minor and non-specific findings. The pathogenesis of VM is uncertain but migraine mechanisms may interfere with the vestibular system at the level of the labyrinth, brainstem and cerebral cortex. Treatment includes vestibular suppressants for acute attacks and migraine prophylaxis for patients with frequent recurrences. Avoidance of triggers, stress management and biofeedback may also play a role. However, treatment efficacy has not been validated by properly controlled clinical trials. VM is not included in the 2004 International Headache Society Classification, where basilar-type migraine must have at least two posterior circulation manifestations so that isolated vertigo would not satisfy this criterion.
前庭性偏头痛(VM)表现为自发性或位置性眩晕发作,持续数秒至数天。急性发作时通常无头痛,但可能出现偏头痛的其他症状,如畏光或先兆。与偏头痛性头痛一样,VM的触发因素可能包括压力、睡眠不足和激素变化。急性发作期间可能出现中枢性自发性或位置性眼球震颤,较少见的是单侧前庭功能减退。在无症状期,前庭测试大多显示轻微和非特异性结果。VM的发病机制尚不确定,但偏头痛机制可能在迷路、脑干和大脑皮层水平干扰前庭系统。治疗包括急性发作时使用前庭抑制剂,以及对频繁复发患者进行偏头痛预防性治疗。避免触发因素、压力管理和生物反馈也可能起作用。然而,治疗效果尚未通过适当对照的临床试验得到验证。VM未被纳入2004年国际头痛协会分类,其中基底型偏头痛必须至少有两种后循环表现,因此孤立性眩晕不符合该标准。