University of Abertay, Dundee, DD1 1HG, UK.
J Bone Miner Metab. 2010 Mar;28(2):185-90. doi: 10.1007/s00774-009-0113-3. Epub 2009 Jul 24.
Although the influence of weight-bearing activity on bone mass has been widely investigated in white women, few studies have been conducted in black, African populations. We investigated bone mineral density (BMD) in black South African women, with and without a history of load-carrying on the head. We also investigated whether load carrying may offer protection against low BMD in users of injectable progestin contraception (IPC). Participants were 32 black, South African women (22.4 +/- 3.2 years). Load carrying history was determined by questionnaire and interview; participants were grouped as load carriers (LC; n = 18) or non-load carriers (NLC; n = 14). Ten women were using IPC and 6 were load-carriers. Total body (TB), lumbar spine (LS) and total hip (H) BMD were measured by dual energy X-ray absorptiometry. There were no differences in BMD between LC and NLC, and after controlling for age and BMI using two-tailed partial correlations. IPC users had lower BMD at all sites compared to non-IPC users (p < 0.05) and there were no associations between load carrying and BMD in this group. When IPC users were excluded from analysis, LC had higher LS BMD than NLC (p < 0.005). Correlations were found between the weight of load carried and LS BMD (r = 0.743, p < 0.005), and between years of load carrying and LS and TB BMD (r = 0.563, r = 0.538, respectively; both p < 0.05). Load carrying on the head may offer osteogenic benefits to the spine but these benefits did not appear in women using IPC.
尽管负重活动对骨量的影响在白人女性中已得到广泛研究，但在黑人、非洲人群中进行的研究较少。我们研究了黑种南非女性的骨密度（BMD），这些女性有的有头部负重史，有的没有。我们还研究了头部负重是否可能为使用注射式孕激素避孕（IPC）的女性提供对低 BMD 的保护。参与者为 32 名黑种南非女性（22.4 ± 3.2 岁）。通过问卷和访谈确定了负重史；参与者分为负重者（LC；n = 18）或非负重者（NLC；n = 14）。10 名女性正在使用 IPC，其中 6 名是负重者。全身（TB）、腰椎（LS）和总髋部（H）BMD 通过双能 X 射线吸收法测量。在控制年龄和 BMI 后，使用双侧部分相关，LC 和 NLC 之间的 BMD 没有差异。与非 IPC 用户相比，IPC 用户在所有部位的 BMD 均较低（p < 0.05），并且在该组中，负重与 BMD 之间没有关联。当从分析中排除 IPC 用户时，LC 的 LS BMD 高于 NLC（p < 0.005）。发现携带的负荷重量与 LS BMD 之间存在相关性（r = 0.743，p < 0.005），以及携带负荷的年数与 LS 和 TB BMD 之间存在相关性（r = 0.563，r = 0.538，分别；均 p < 0.05）。头部负重可能对脊柱有促骨生成的益处，但这些益处并未出现在使用 IPC 的女性中。
