一种用于量化大鼠神经病理性疼痛行为的电生理学方法：测量后肢撤回 EMG 幅度。
An electrophysiological method for quantifying neuropathic pain behaviors in rats: measurement of hindlimb withdrawal EMG magnitude.
机构信息
Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX 77555-1069, USA.
出版信息
J Physiol Sci. 2009 Nov;59(6):473-6. doi: 10.1007/s12576-009-0051-9. Epub 2009 Jul 24.
Abstract
In behavior methods to quantify neuropathic pain, visual observations of limb-withdrawal reflexes to stimuli are not always clear-cut, so this method is partly subjective. Our current data suggest that measurement of electrophysiological EMG magnitudes enables more reliable and objective assessment for quantifying nocifensive behaviors related to neuropathic pain.
摘要
在量化神经性疼痛的行为方法中，对刺激的肢体退缩反射的视觉观察并不总是清晰明确的，因此这种方法在一定程度上具有主观性。我们目前的数据表明，测量电生理 EMG 幅度可更可靠、更客观地评估与神经性疼痛相关的伤害性行为。
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