Selective identification of cooperatively binding fragments in a high-throughput ligation assay enables development of a picomolar caspase-3 inhibitor.
作者信息
Schmidt Marco F, El-Dahshan Adeeb, Keller Sandro, Rademann Jörg
机构信息
Leibniz Institute of Molecular Pharmacology (FMP), Robert-Rössle-Strasse 10, 13125 Berlin, Germany.
出版信息
Angew Chem Int Ed Engl. 2009;48(34):6346-9. doi: 10.1002/anie.200901647.