Geerts W
Thromboembolism Program, Sunnybrook Health Sciences Centre, Department of Medicine, University of Toronto, Toronto, ON, Canada.
J Thromb Haemost. 2009 Jul;7 Suppl 1:1-8. doi: 10.1111/j.1538-7836.2009.03384.x.
It is more than 50 years since the first publication of a study showing that symptomatic and fatal venous thromboembolism could be reduced with the use of thromboprophylaxis. Furthermore, it is 23 years since the first evidence-based guidelines recommended routine use of thromboprophylaxis for most hospitalized patients. However, despite the overwhelming evidence that thromboprophylaxis safely and inexpensively reduces thromboembolic complications associated with acute illness and surgery, there continue to be large gaps in the provision of this key patient safety intervention and even larger gaps in the provision of optimal thromboprophylaxis. The implementation of quality improvement strategies, both at the national level and in local hospitals, are able to increase awareness of thromboembolic risks, to increase adherence to thromboprophylaxis guidelines, and to decrease both clinically important thromboembolic events and hospital costs. Therefore, the objective is for every hospitalized patient to receive appropriate thromboprophylaxis based on their thromboembolic and bleeding risks.
自首次发表一项研究表明使用血栓预防措施可降低有症状和致命性静脉血栓栓塞以来，已过去50多年。此外，自首个基于证据的指南推荐对大多数住院患者常规使用血栓预防措施以来，也已过去23年。然而，尽管有压倒性的证据表明血栓预防措施能安全且经济地减少与急性疾病和手术相关的血栓栓塞并发症，但在提供这一关键的患者安全干预措施方面仍存在巨大差距，在提供最佳血栓预防措施方面的差距甚至更大。在国家层面和当地医院实施质量改进策略，能够提高对血栓栓塞风险的认识，增加对血栓预防指南的依从性，并减少具有临床重要意义的血栓栓塞事件和医院成本。因此，目标是让每一位住院患者根据其血栓栓塞和出血风险接受适当的血栓预防措施。
