Limperopoulos Catherine, Clouchoux Cedric
Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.
Semin Perinatol. 2009 Aug;33(4):289-98. doi: 10.1053/j.semperi.2009.04.002.
Fetal MRI is becoming an increasingly powerful imaging tool for studying brain development in vivo. Until recently, the application of advanced magnetic resonance imaging techniques was limited by motion in the nonsedated fetus. Extensive research efforts currently underway are focusing on the development of dedicated magnetic resonance imaging sequences and sophisticated postprocessing techniques that are revolutionizing our ability to study the healthy and compromised fetus. The ongoing refinement of these magnetic resonance imaging techniques will undoubtedly lead to the development of cornerstone biomarkers that will provide healthcare caregivers with vital, and currently lacking, information upon which to counsel parents effectively, and base rational decisions regarding the timing and type of novel medical and surgical interventions currently on the horizon.
胎儿磁共振成像正日益成为一种强大的成像工具，用于在体研究大脑发育。直到最近，先进磁共振成像技术的应用还受到未镇静胎儿运动的限制。目前正在进行的大量研究工作聚焦于开发专用的磁共振成像序列和复杂的后处理技术，这些技术正在彻底改变我们研究健康和受损胎儿的能力。这些磁共振成像技术的不断完善无疑将导致基石生物标志物的开发，这将为医护人员提供至关重要且目前缺乏的信息，以便有效地为父母提供咨询，并为有关当前即将出现的新型医疗和外科干预的时机和类型做出合理决策提供依据。
