Saran M, Michel C, Bors W
Institut für Strahlenbiologie, GSF Research Center, Neuherberg, W. Germany.
Free Radic Res Commun. 1990;10(4-5):221-6. doi: 10.3109/10715769009149890.
Under physiological pH conditions (pH 7.2-7.4) the rate constant of the reaction NO + O2- yielding peroxonitrite (ONOO-) was determined as k = (3.7 +/- 1.1) x 10(7) M-1 s-1. The decay of peroxonitrite at this pH follows first order kinetics with a rate constant of 1.4 s 1. At alkaline pH peroxonitrite is practically stable. Possible consequences of these reactions for the biological lifetime of EDRF will be discussed.
在生理pH条件（pH 7.2 - 7.4）下，反应NO + O2-生成过氧亚硝酸盐（ONOO-）的速率常数测定为k = (3.7 ± 1.1) x 10(7) M-1 s-1。在此pH值下，过氧亚硝酸盐的衰变遵循一级动力学，速率常数为1.4 s-1。在碱性pH条件下，过氧亚硝酸盐实际上是稳定的。将讨论这些反应对内皮舒张因子（EDRF）生物学寿命的可能影响。
