Zhao Jinna, Li Ying, Wu Yulin, Zhou Jian, Ba Lei, Gu Xiaoping, Wang Weidong, Yao Hui, Ren Naixiu, Chen Jianhong, Xu Lianfang
Department of Epidemiology and Biostatistics, Nanjing Medical University, Nanjing 210029, China.
Contraception. 2009 Aug;80(2):180-6. doi: 10.1016/j.contraception.2009.02.002. Epub 2009 Apr 5.
The combined oral contraceptives (COCs) and intrauterine devices (IUDs) are the most common contraceptive methods used by women. Women's choices of contraceptive method are largely affected by the safety and efficacy of contraceptive methods as well as by change in women's quality of life. However, there are still scanty data focusing on the impact of COC or IUD on quality of life in women, especially in China. The aim of this study was to evaluate the impact of desogestrel and ethinyl estradiol tablets (Marvelon) and Yuangong-Cu220 IUD (YCu220 IUD) on quality of life in rural women of the Jiangsu province in China.
In this prospective cohort study, 784 COC users and 910 YCu220 IUD users were included. The women filled up quality-of-life questionnaires (Quality of Life Enjoyment and Satisfaction Questionnaire) before and after use of contraceptive methods.
Significant score changes in physical health, mood, work/school/labor, living situation, vision, general well-being and overall satisfaction were noted as significant improvements after COC use in women (p<.05), and the largest improvements were in physical health and living situation; all item scores except for work/school/labor, household activities and leisure time activities had improved statistically from baseline in YCu220 IUD users (p<.05). For COC users, the proportions of women with total quality-of-life scores >/=57 before and after COC use were 11.50% and 11.79%, respectively; but the proportion of YCu220 IUD users with total quality-of-life scores >/=57 increased from 4.40% to 12.04%. Compared to women without contraceptive use history, women with past OC and/or IUD use had a significantly higher difference in the total quality-of-life scores.
COC and YCu220 IUD could significantly improve overall quality of life in rural women of the Jiangsu province.
复方口服避孕药（COC）和宫内节育器（IUD）是女性最常用的避孕方法。女性对避孕方法的选择很大程度上受避孕方法的安全性和有效性以及女性生活质量变化的影响。然而，关于COC或IUD对女性生活质量影响的数据仍然很少，尤其是在中国。本研究的目的是评估去氧孕烯炔雌醇片（妈富隆）和元宫铜220宫内节育器（YCu220 IUD）对中国江苏省农村女性生活质量的影响。
在这项前瞻性队列研究中，纳入了784名COC使用者和910名YCu220 IUD使用者。这些女性在使用避孕方法前后填写了生活质量问卷（生活质量享受与满意度问卷）。
女性使用COC后，在身体健康、情绪、工作/学校/劳动、生活状况、视力、总体幸福感和总体满意度方面的得分有显著变化，显示出显著改善（p<0.05），最大的改善在身体健康和生活状况方面；YCu220 IUD使用者除工作/学校/劳动、家务活动和休闲时间活动外，所有项目得分均较基线有统计学意义的改善（p<0.05）。对于COC使用者，使用COC前后生活质量总得分≥57分的女性比例分别为11.50%和11.79%；但YCu220 IUD使用者生活质量总得分≥57分的比例从4.40%增加到12.04%。与无避孕使用史的女性相比，既往使用过OC和/或IUD的女性在生活质量总得分上有显著更高的差异。
COC和YCu220 IUD可显著改善江苏省农村女性的总体生活质量。
