Washington University School of Medicine, Barnes-Jewish Hospital, Division of Cardiothoracic Surgery, Saint Louis, Missouri 63110, USA.
Heart Rhythm. 2009 Aug;6(8 Suppl):S45-50. doi: 10.1016/j.hrthm.2009.05.019. Epub 2009 May 22.
For two decades, the cut-and-sew Cox-maze III procedure was the gold standard for the surgical treatment of atrial fibrillation (AF) and has proven to be effective at eliminating AF. The incidence of late stroke was also very low. However, this procedure was not widely adopted owing to its complexity and technical difficulty. Over the last 5-10 years, the introduction of new ablation technology has led to the development of the Cox-maze IV procedure as well as more limited lesion sets, with the ultimate goal of performing a minimally invasive lesion set on the beating heart without the need for cardiopulmonary bypass. This review summarizes the current state of the art and future directions in the stand-alone surgical treatment of AF. The hope is that as more is learned about the mechanisms of AF and with better preoperative diagnostic technologies capable of precisely locating the areas responsible for AF, it will become possible to tailor specific lesion sets and ablation modalities to individual patients, making the surgical treatment of AF available to a larger population of patients.
二十年来,心迷宫 III 切开缝合术一直是心房颤动 (AF) 外科治疗的金标准,已被证明能有效消除 AF。晚期中风的发生率也非常低。然而,由于其复杂性和技术难度,该手术并未广泛采用。在过去的 5-10 年中,新的消融技术的引入导致了心迷宫 IV 手术以及更有限的病变集的发展,其最终目标是在不进行体外循环的情况下在心搏中进行微创病变集。本综述总结了孤立性房颤外科治疗的现状和未来方向。希望随着对房颤机制的更多了解,以及具有更精确定位房颤责任区域的术前诊断技术的发展,能够为每位患者量身定制特定的病变集和消融方式,使更多的房颤患者能够接受手术治疗。