Lococo Filippo, Cesario Alfredo, Meacci Elisa, Cusumano Giacomo, Margaritora Stefano
Department of Thoracic Surgery, Catholic University and Scientific Direction, Rome, Italy.
Ann Thorac Surg. 2009 Aug;88(2):e9-10. doi: 10.1016/j.athoracsur.2009.05.018.
A young woman was referred to our institution for the appearance of a single pulmonary nodule at a routine follow-up computed tomographic scan of the thorax. She had been operated on 4 years earlier for a parachordoma of the iliopsoas muscle. Wedge resections were accessed through a mini-thoracotomy, and the pathologic examination confirmed the diagnosis of parachordoma lung metastases. Adjuvant chemotherapy (Glivec, 400 mg/daily [imatinib; Novartis, Basel, Switzerland]) was indicated and was administered for 10 months. At the time this case report was written, the patient was alive with no sign of tumor recurrence. We believe that metastatic parachordoma to the lung has been previously reported only once in the English literature. Our case adds evidence that parachordoma, despite its generally indolent behavior, can metastasize to the lung.
一名年轻女性在胸部常规随访计算机断层扫描中发现单个肺结节后被转诊至我院。她4年前因髂腰肌副脊索瘤接受了手术。通过小切口开胸进行楔形切除术，病理检查确诊为副脊索瘤肺转移。给予辅助化疗（格列卫，400mg/每日[伊马替尼；瑞士巴塞尔诺华公司]），持续10个月。在撰写本病例报告时，患者存活，无肿瘤复发迹象。我们认为，肺转移性副脊索瘤此前在英文文献中仅被报道过一次。我们的病例进一步证明，尽管副脊索瘤通常生长缓慢，但仍可转移至肺部。
