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再次手术行内镜下交感神经切除术治疗持续性或复发性手掌多汗症。

Reoperative endoscopic sympathectomy for persistent or recurrent palmar hyperhidrosis.

作者信息

Freeman Richard K, Van Woerkom Jaclyn M, Vyverberg Amy, Ascioti Anthony J

机构信息

Department of Thoracic and Cardiovascular Surgery, St Vincent Hospital, Indianapolis, Indiana, USA.

出版信息

Ann Thorac Surg. 2009 Aug;88(2):412-6; discussion 416-7. doi: 10.1016/j.athoracsur.2009.03.101.

Abstract

BACKGROUND

Sympathectomy for severe palmar hyperhidrosis occasionally fails. This investigation reviews our experience with reoperative thoracoscopic sympathectomy (RS) for patients with persistent or recurrent palmar hyperhidrosis after sympathectomy.

METHODS

A retrospective analysis of patients undergoing RS for palmar hyperhidrosis was conducted. Comparison was made with all patients undergoing an initial thoracoscopic sympathectomy (TS) for palmar hyperhidrosis at our institution during the same period.

RESULTS

Over 6 years, 40 patients underwent bilateral (32) or unilateral (8) RS for refractory (35) or recurrent (5) palmar hyperhidrosis. During the same period, 321 patients underwent bilateral TS for palmar hyperhidrosis. Previous methods of sympathectomy included percutaneous ablation (25), TS (10), axillary thoracotomy (3), and a posterior transthoracic approach (2). Twenty-two RS patients and 11 TS patients required a third port to complete the procedure because of pleural adhesions (p = 0.0001). Twenty-three RS and 11 TS patients required postoperative pleural drainage (p = 0.0004). Mean length of stay was1.6 for the RS group and less than 1 day for the TS group (p = 0.0001). Alleviation of palmar hyperhidrosis occurred in 38 RS patients and 316 TS patients (p = 0.18). Compensatory sweating was identified in 21 RS patients and 101 TS patients (p = 0.01).

CONCLUSIONS

Reoperative thoracoscopic sympathectomy produced a rate of improvement comparable to that of TS. However, RS was associated with an increased need for postoperative pleural drainage, longer hospital stay, a more difficult operative procedure, and a higher rate of compensatory sweating than TS was. Reoperative sympathectomy should be considered a safe and effective option for patients with palmar hyperhidrosis who remain severely symptomatic after a sympathectomy.

摘要

背景

交感神经切除术治疗重度手掌多汗症偶尔会失败。本研究回顾了我们对交感神经切除术后持续性或复发性手掌多汗症患者进行再次胸腔镜交感神经切除术(RS)的经验。

方法

对接受RS治疗手掌多汗症的患者进行回顾性分析。与同期在本机构接受初次胸腔镜交感神经切除术(TS)治疗手掌多汗症的所有患者进行比较。

结果

在6年期间,40例患者因难治性(35例)或复发性(5例)手掌多汗症接受了双侧(32例)或单侧(8例)RS。同期,321例患者接受了双侧TS治疗手掌多汗症。既往交感神经切除术方法包括经皮消融(25例)、TS(10例)、腋下开胸术(3例)和后胸廓切开术(2例)。由于胸膜粘连,22例RS患者和11例TS患者需要第三个切口来完成手术(p = 0.0001)。23例RS患者和11例TS患者术后需要胸腔引流(p = 0.0004)。RS组平均住院时间为1.6天,TS组少于1天(p = 0.0001)。38例RS患者和316例TS患者手掌多汗症得到缓解(p = 0.18)。21例RS患者和101例TS患者出现代偿性出汗(p = 0.01)。

结论

再次胸腔镜交感神经切除术的改善率与TS相当。然而,与TS相比,RS术后胸腔引流需求增加、住院时间延长、手术操作更困难且代偿性出汗发生率更高。对于交感神经切除术后仍有严重症状的手掌多汗症患者,再次交感神经切除术应被视为一种安全有效的选择。

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