Department of Neurosurgery, Medical University Hannover, Hannover, Germany.
Eur J Surg Oncol. 2010 Feb;36(2):208-13. doi: 10.1016/j.ejso.2009.07.004. Epub 2009 Jul 26.
The microsurgical resection of tumors or vascular lesions in the cavernous sinus and the neighbouring Meckel's cave has been considered as hazardous because of often associated cranial nerve morbidity. Despite increasing consent that many of such tumors should not undergo surgical therapy, the cavernous sinus and Meckel's cave may harbour small lesions of various origin, which are amenable for surgical resection. Surgery in this anatomical area needs a well directed approach. In this setting, neuronavigational guidance may provide a useful tool. We report on a series of patients operated on and guided by neuronavigation.
Five patients underwent a pterional approach for microsurgical resection. The procedures were planned and assisted by a pointer based neuronavigation system (Medtronic Stealth Station). Pathological entities included schwannoma, epidermoid, cavernoma and capillary hemangioma. Three lesions were located in the Meckel's cave and two lesions in the cavernous sinus.
Intraoperative guidance by neuronavigation appeared to be particularly instrumental in identification of the appropriate site of dural incision over the target region for microsurgical resection. Except of a mild increase of facial hypesthesia in one patient, there were no new cranial nerve deficits. In three patients, preoperative symptoms improved immediately after surgery.
The surgical resection of small tumors or vascular lesions within the Meckel's cave or cavernous sinus is facilitated by neuronavigational guidance with sufficient intraoperative reliability and safety. In consideration of well known anatomical landmarks, targeted entry into the cavernous sinus or Meckel's cave directed by neuronavigation enables a tailored approach for microsurgical resection.
由于常伴有颅神经损伤,海绵窦和邻近的 Meckel 腔中肿瘤或血管病变的显微切除术被认为是危险的。尽管越来越多的人同意许多此类肿瘤不应进行手术治疗,但海绵窦和 Meckel 腔可能存在各种来源的小病变,这些病变适合手术切除。在这个解剖区域进行手术需要一个明确的方法。在这种情况下,神经导航可能提供一种有用的工具。我们报告了一系列接受神经导航指导手术的患者。
五例患者接受翼点入路显微切除术。手术由基于指针的神经导航系统(美敦力 Stealth Station)进行规划和辅助。病变包括神经鞘瘤、表皮样囊肿、海绵状血管瘤和毛细血管血管瘤。三个病变位于 Meckel 腔,两个病变位于海绵窦。
神经导航的术中引导似乎特别有助于确定在目标区域进行显微切除的合适硬脑膜切口部位。除了一名患者出现轻度面部感觉减退外,没有新的颅神经损伤。在三名患者中,术前症状在手术后立即改善。
神经导航辅助下,海绵窦或 Meckel 腔内部的小肿瘤或血管病变的手术切除更方便,具有足够的术中可靠性和安全性。考虑到已知的解剖标志,通过神经导航靶向进入海绵窦或 Meckel 腔,为显微切除术提供了一种针对性的方法。