脊髓灰质炎病毒介导的商陆抗病毒蛋白的进入。
Poliovirus-mediated entry of pokeweed antiviral protein.
作者信息
Lee T, Crowell M, Shearer M H, Aron G M, Irvin J D
机构信息
Department of Biology, Southwest Texas State University, San Marcos 78666.
出版信息
Antimicrob Agents Chemother. 1990 Oct;34(10):2034-7. doi: 10.1128/AAC.34.10.2034.
Abstract
Infection of HeLa cells with poliovirus results in cell permeabilization to pokeweed antiviral protein. Cell permeabilization was dependent on the integrity of virus capsid proteins and directly proportional to the multiplicity of infection. This study demonstrates that virus adsorption is sufficient for the entry of pokeweed antiviral protein into poliovirus-infected cells.
摘要
用脊髓灰质炎病毒感染HeLa细胞会导致细胞对商陆抗病毒蛋白通透。细胞通透取决于病毒衣壳蛋白的完整性，且与感染复数成正比。本研究表明病毒吸附足以使商陆抗病毒蛋白进入脊髓灰质炎病毒感染的细胞。
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