鸡的劳斯肉瘤：生长增强与伴随免疫共存。
Rous sarcomas in chickens: enhanced growth coexisting with concomitant immunity.
作者信息
McBride R A, Watanabe D H, Schierman L W
出版信息
Science. 1977 Sep 9;197(4308):1079-82. doi: 10.1126/science.196336.
PMID:196336
Abstract
Chickens bearing Rous sarcoma virus-induced tumors in one wing did not develop new tumors when subsequently inoculated with Rous sarcoma virus in the other wing. However, the second inoculation of Rous sarcoma virus caused accelerated growth of the established tumors. This phenomenon was found to be bursa-dependent. Paradoxically, established tumors in bursectomized chickens grew at a diminished rate if the chickens were reinoculated with Rous sarcoma virus.
摘要
一侧翅膀带有劳氏肉瘤病毒诱导肿瘤的鸡，当随后在另一侧翅膀接种劳氏肉瘤病毒时，不会长出新的肿瘤。然而，再次接种劳氏肉瘤病毒会使已有的肿瘤加速生长。这一现象被发现依赖于法氏囊。矛盾的是，如果对接种过劳氏肉瘤病毒的切除法氏囊的鸡再次接种该病毒，已有的肿瘤生长速度会减慢。
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