Lewin A A, Abitbol A A, Schwade J G, Osman D, DerHagopian R, Ostroski J, Serago C, Houdek P, Bujnoski J
Baptist Hospital of Miami, Regional Cancer Treatment Center 33256.
J Fla Med Assoc. 1990 Dec;77(12):1034-6.
Conservative surgery and radiation therapy were used to treat 212 patients with AJC clinical Stage I or II breast carcinoma at the Baptist Hospital of Miami. All had lumpectomy and most axillary lymph node dissection, followed by breast irradiation to a dose of 45 Gy and a boost dose of 14 to 16 Gy to the surgical bed. Median follow-up was 55 months. The five-year actuarial local control and survival rates were 94% and 86% respectively. Eighty-six percent of the patients had excellent or good cosmetic results with minimal differences between the treated and untreated breasts. Treatment-related complications were minor and infrequent. These results appear comparable to retrospective reviews at major university centers and ongoing prospective randomized trials.
迈阿密浸信会医院采用保守性手术和放射治疗对212例AJC临床I期或II期乳腺癌患者进行治疗。所有患者均接受了肿块切除术，多数患者进行了腋窝淋巴结清扫术，随后对乳房进行照射，剂量为45 Gy，并对手术床追加14至16 Gy的剂量。中位随访时间为55个月。五年精算局部控制率和生存率分别为94%和86%。86%的患者获得了优异或良好的美容效果，治疗侧乳房与未治疗侧乳房之间差异极小。与治疗相关的并发症轻微且不常见。这些结果与主要大学中心的回顾性研究以及正在进行的前瞻性随机试验结果相当。
