Salti Haytham I, Nasrallah Mona, Haddad Sandra, Khairallah Walid, Salti I S
Department of Ophthalmology, American University of Beirut Medical Center, Beirut, Lebanon.
Ophthalmic Surg Lasers Imaging. 2009 Jul-Aug;40(4):373-8. doi: 10.3928/15428877-20096030-04.
Nonmydriatic digital color imaging is rapidly gaining an important role in screening for diabetic retinopathy. However, it has yet to equal a dilated fundus examination or seven Early Treatment Diabetic Retinopathy Study field 35-mm photography. The authors therefore attempted to enhance efficacy and validity by adding two low-cost steps to the nonmydriatic digital image evaluation.
The fundi of 145 consecutive patients with diabetes mellitus were evaluated for diabetic retinopathy using two different nonmydriatic reading techniques: creating a red-free view (using digital filters) and looking at a stereo pair of each field taken. These methods were each compared to a mydriatic fundus examination.
Although the first technique yielded views with sensitivities and specificities similar to what exists in the literature using this same technique, enhancing these photographs (second technique) yielded a statistically significant increase in sensitivity and specificity (P < .005).
The authors recommend using both low-cost steps when screening for diabetic retinopathy through nonmydriatic digital color imaging.
非散瞳数字彩色成像在糖尿病视网膜病变筛查中迅速占据重要地位。然而，它仍无法与散瞳眼底检查或七张糖尿病视网膜病变早期治疗研究（ETDRS）35毫米视野照片相媲美。因此，作者试图通过在非散瞳数字图像评估中增加两个低成本步骤来提高其有效性和准确性。
使用两种不同的非散瞳阅读技术对145例连续糖尿病患者的眼底进行糖尿病视网膜病变评估：创建无赤光视图（使用数字滤镜）以及查看每个视野的立体图像对。将这些方法分别与散瞳眼底检查进行比较。
尽管第一种技术所获得图像的敏感性和特异性与使用该技术的文献报道相似，但对这些照片进行增强处理（第二种技术）后，敏感性和特异性在统计学上有显著提高（P < .005）。
作者建议在通过非散瞳数字彩色成像筛查糖尿病视网膜病变时采用这两个低成本步骤。
