Kinkel Stefan, Stecher Jens, Gotterbarm Tobias, Bruckner Thomas, Holz Ulrich
Orthopaedic University Clinic Heidelberg, Schlierbacher Landstr 200a, 69118 Heidelberg, Germany.
Orthopedics. 2009 Jun;32(6):403. doi: 10.3928/01477447-20090511-14.
Due to improved oncological therapeutic procedures with longer survival times, the stabilization of osteolyses and pathological fractures is gaining importance. The proximal femur is often affected by metastases. As femoral stability can be compromised by such bone lesions, stabilization as a palliative measure is indicated to restore function and relieve pain. Besides intramedullary osteosynthesis and endoprosthetic reconstruction, compound osteosynthesis is an alternative method for stabilization of the proximal femur. Between 1994 and 2004, 34 compound osteosyntheses were performed for a tumor-caused lesion compromising mechanical stability of the proximal femur. Of those cases, 22 double-plate compound osteosyntheses and 12 single-plate compound osteosyntheses were performed for 9 pathological fractures and 25 osteolyses. Both techniques provided good primary stability. The average survival time after compound osteosynthesis was 14.2 months (range, 0-72 months). Double-plate compound osteosyntheses showed a lower mechanical failure rate than single-plate compound osteosyntheses (14.3% vs 33.3%) and a higher survival probability after 5 years (76.4% vs 38.6%). No surgical revision was required due to perioperative complications in any case. We conclude that reliable stabilization of extensive osteolyses and pathological fractures of the proximal femur can be achieved with compound osteosynthesis. Our data suggest that double-plate compound osteosyntheses is a more favorable technique than single-plate compound osteosyntheses based on a lower rate of mechanical failure and higher survival probability.
由于肿瘤治疗手段的改进使患者生存时间延长,骨溶解和病理性骨折的稳定处理变得愈发重要。股骨近端常受转移瘤影响。此类骨病变会损害股骨稳定性,因此需采取稳定化的姑息治疗措施来恢复功能并减轻疼痛。除髓内骨固定术和假体置换重建外,复合骨固定术是稳定股骨近端的另一种方法。1994年至2004年间,针对导致股骨近端机械稳定性受损的肿瘤性病变进行了34例复合骨固定术。其中,针对9例病理性骨折和25例骨溶解分别实施了22例双钢板复合骨固定术和12例单钢板复合骨固定术。两种技术均提供了良好的初始稳定性。复合骨固定术后的平均生存时间为14.2个月(范围0 - 72个月)。双钢板复合骨固定术的机械故障率低于单钢板复合骨固定术(14.3%对33.3%),且5年后的生存概率更高(76.4%对38.6%)。在任何情况下,均未因围手术期并发症而需要进行手术翻修。我们得出结论,复合骨固定术可实现股骨近端广泛骨溶解和病理性骨折的可靠稳定。我们的数据表明,基于较低的机械故障率和较高的生存概率,双钢板复合骨固定术是比单钢板复合骨固定术更优的技术。