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酒精性股骨头坏死的全髋关节置换术。

Total hip arthroplasty for alcoholic osteonecrosis of the femoral head.

作者信息

Yuan Brandon, Taunton Michael J, Trousdale Robert T

机构信息

Mayo Clinic, Rochester, Minnesota 55905, USA.

出版信息

Orthopedics. 2009 Jun;32(6):400. doi: 10.3928/01477447-20090511-06.

Abstract

Osteonecrosis of the femoral head in the setting of alcohol abuse is a potential important cause of symptomatic hip disease in young patients. All cases of uncemented primary total hip arthroplasty (THA) with a primary operative diagnosis of osteonecrosis of the femoral head secondary to alcohol abuse treated at our institution from January 1990 to February 2002 were identified. Twenty-three patients with 28 hips were identified; all patients had advanced disease (subchondral collapse) that was unresponsive to conservative treatment modalities. Within 5 years of index THA, 2 patients were lost to follow-up, and 2 patients died from causes unrelated to their surgery. The remaining 19 patients underwent 24 THAs. Unilateral THA was performed in 14 patients, and bilateral THA was performed in 5 patients. Seventeen men and 2 women with an average age of 41.8 years (range, 30-59 years) at the time of THA were included in the study. The average duration to clinical follow-up was 7.6 years. There was significant improvement in hip pain and hip function scores. Seven THAs were revised at a mean 6.7 years following index THA. Five- and 10-year implant survivorship free of revision was 96% and 64%, respectively (Kaplan-Meier Survivorship Analysis). The continued use of alcohol was associated with a slightly increased risk of failure (61% implant survivorship at 10 years in those with continued alcohol intake vs 75% 10-year survivorship in those without).

摘要

酗酒所致股骨头坏死是年轻患者出现症状性髋关节疾病的一个潜在重要原因。我们确定了1990年1月至2002年2月在我院接受治疗的所有初次非骨水泥型全髋关节置换术(THA)病例,这些病例的主要手术诊断为酗酒继发的股骨头坏死。共确定了23例患者的28个髋关节;所有患者均患有晚期疾病(软骨下塌陷),对保守治疗方式无反应。在初次THA后的5年内,2例患者失访,2例患者死于与手术无关的原因。其余19例患者接受了24次THA。14例患者接受了单侧THA,5例患者接受了双侧THA。研究纳入了17名男性和2名女性,初次THA时的平均年龄为41.8岁(范围为30 - 59岁)。临床随访的平均时长为7.6年。髋关节疼痛和髋关节功能评分有显著改善。在初次THA后的平均6.7年,7次THA进行了翻修。无翻修的5年和10年植入物生存率分别为96%和64%(Kaplan-Meier生存率分析)。持续饮酒与失败风险略有增加相关(持续饮酒者10年时植入物生存率为61%,而不饮酒者为75%)。

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