Vicaş Răzvan Marius, Bodog Florian Dorel, Ciursaş Adina Nicoleta, Fugaru Ovidiu Florin, Grosu Florin, Lazăr Liviu, Nistor Cseppento Carmen Delia, Beiuşanu Gabriela Corina, Buzlea Călin David, Ţică Ovidiu, Brihan Ilarie, Zdrîncă Mihaela
Department of Morphological Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, Romania.
Department of Surgery, Faculty of Medicine and Pharmacy, University of Oradea, Romania.
Curr Health Sci J. 2021 Apr-Jun;47(2):228-236. doi: 10.12865/CHSJ.47.02.13. Epub 2021 Jun 30.
Femoral head osteonecrosis is a disease characterized by the decrease of blood vascularization in the femoral head, which leads to death of the osteocytes, demineralization and resorption of bone spans, change of trabecular architecture, with the reduction of the bone mechanical resistance and collapse of the articular surface in the femoral head. Left untreated, the disease may have a rapid progression, leading to severe symptoms, with significant articular dysfunction, functional impotence and a serious impact on the patient's quality of life. The prevalence of the disease is ever growing all over the world, affecting mainly people in their 30s, 40s or 50s. In the present study, we analyzed a number of 76 patients with femoral head osteonecrosis with severe symptoms that required a surgical treatment. There was observed that more than ¾ of the investigated patients were males, while 81.58% were younger than 60 years old. Among the identified risk factors, smoking came first, followed by alcohol intake, obesity and chronic administration of corticosteroids. A very high percentage of patients (84.21%) were diagnosed in stages III and IV of the disease.
股骨头坏死是一种以股骨头血管化减少为特征的疾病，这会导致骨细胞死亡、骨小梁脱矿和吸收、小梁结构改变，进而导致股骨头骨机械阻力降低和关节面塌陷。若不治疗，该病可能迅速发展，导致严重症状，出现明显的关节功能障碍、功能丧失，并对患者的生活质量产生严重影响。该病在全球的患病率不断上升，主要影响30多岁、40多岁或50多岁的人群。在本研究中，我们分析了76例有严重症状且需要手术治疗的股骨头坏死患者。结果发现，超过四分之三的被调查患者为男性，81.58%的患者年龄小于60岁。在已确定的风险因素中，吸烟居首，其次是饮酒、肥胖和长期使用皮质类固醇。很高比例的患者（84.21%）在疾病的III期和IV期被诊断出来。
