Heckers Stephan
Vanderbilt University Psychiatric Hospital, 1601 23rd Avenue South, Room 3060, Nashville, TN 37212, USA.
Curr Psychiatry Rep. 2009 Aug;11(4):332-7. doi: 10.1007/s11920-009-0048-3.
A diagnosis of schizoaffective disorder is frequently used to describe a psychotic person with significant symptoms of depression and/or mania. The word schizoaffective was introduced by Jacob Kasanin in 1933 and has appeared in all editions of the DSM since 1952. However, the current DSM-IV-TR diagnosis of schizoaffective disorder is not reliable and is of limited clinical utility. The validity is built primarily on the prediction of course and outcome and on emerging findings from genetic and neurobiological studies. This review of the current status of schizoaffective disorder concludes with several suggestions for a revision of the diagnosis within a categorical or dimensional nosology of psychotic and affective disorders.
精神分裂症伴情感障碍的诊断常被用于描述有明显抑郁和/或躁狂症状的精神病患者。“精神分裂症伴情感障碍”一词由雅各布·卡沙宁于1933年提出，自1952年起出现在所有版本的《精神疾病诊断与统计手册》中。然而，当前《精神疾病诊断与统计手册第四版修订版》（DSM-IV-TR）对精神分裂症伴情感障碍的诊断并不可靠，临床实用性有限。其效度主要建立在病程和预后的预测以及遗传学和神经生物学研究的新发现之上。本文对精神分裂症伴情感障碍的现状进行综述，并就精神病性和情感性障碍的分类或维度分类学中该诊断的修订提出了若干建议。
