Analysis of the gene coding for the BRCA2-interacting protein PALB2 in familial and sporadic pancreatic cancer.
作者信息
Tischkowitz Marc D, Sabbaghian Nelly, Hamel Nancy, Borgida Ayelet, Rosner Chaim, Taherian Nassim, Srivastava Archana, Holter Spring, Rothenmund Heidi, Ghadirian Parviz, Foulkes William D, Gallinger Steven
出版信息
Gastroenterology. 2009 Sep;137(3):1183-6. doi: 10.1053/j.gastro.2009.06.055. Epub 2009 Jul 25.
Abstract
摘要
相似文献
1
Analysis of the gene coding for the BRCA2-interacting protein PALB2 in familial and sporadic pancreatic cancer.家族性和散发性胰腺癌中与BRCA2相互作用蛋白PALB2编码基因的分析。
Gastroenterology. 2009 Sep;137(3):1183-6. doi: 10.1053/j.gastro.2009.06.055. Epub 2009 Jul 25.
2
Contribution of germline mutations in the BRCA and PALB2 genes to pancreatic cancer in Italy.意大利人群中胚系 BRCA 和 PALB2 基因突变对胰腺癌的贡献。
Fam Cancer. 2012 Mar;11(1):41-7. doi: 10.1007/s10689-011-9483-5.
3
BRCA1, BRCA2, PALB2, and CDKN2A mutations in familial pancreatic cancer: a PACGENE study.家族性胰腺癌中BRCA1、BRCA2、PALB2和CDKN2A突变：一项PACGENE研究。
Genet Med. 2015 Jul;17(7):569-77. doi: 10.1038/gim.2014.153. Epub 2014 Nov 20.
4
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene.外显子组测序确定PALB2为胰腺癌易感基因。
Science. 2009 Apr 10;324(5924):217. doi: 10.1126/science.1171202. Epub 2009 Mar 5.
5
PALB2 analysis in BRCA2-like families.PALB2 分析在 BRCA2 样家族中。
Breast Cancer Res Treat. 2011 Jun;127(2):357-62. doi: 10.1007/s10549-010-1001-1. Epub 2010 Jun 26.
6
PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene.PALB2编码一种与BRCA2相互作用的蛋白质，是一种乳腺癌易感基因。
Nat Genet. 2007 Feb;39(2):165-7. doi: 10.1038/ng1959. Epub 2006 Dec 31.
7
PALB2 mutations in European familial pancreatic cancer families.欧洲家族性胰腺癌家系中的 PALB2 突变。
Clin Genet. 2010 Nov;78(5):490-4. doi: 10.1111/j.1399-0004.2010.01425.x.
8
A PALB2 germline mutation associated with hereditary breast cancer in Italy.意大利遗传性乳腺癌相关的 PALB2 种系突变。
Fam Cancer. 2010 Jun;9(2):181-5. doi: 10.1007/s10689-009-9295-z. Epub 2009 Sep 18.
9
Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains.家族性胰腺癌的小鼠模型：Palb2、Brca1 和 Brca2 基因突变小鼠系中肿瘤的组织病理学、潜伏期和药物敏感性。
PLoS One. 2019 Dec 26;14(12):e0226714. doi: 10.1371/journal.pone.0226714. eCollection 2019.
10
PALB2 links BRCA1 and BRCA2 in the DNA-damage response.在DNA损伤反应中，PALB2将BRCA1和BRCA2联系起来。
Curr Biol. 2009 Mar 24;19(6):524-9. doi: 10.1016/j.cub.2009.02.018. Epub 2009 Mar 5.
引用本文的文献
1
Alu-Mediated Duplication and Deletion of Exon 11 Are Frequent Mechanisms of Inactivation, Predisposing Individuals to Hereditary Breast-Ovarian Cancer Syndrome.Alu介导的第11外显子重复和缺失是导致失活的常见机制，使个体易患遗传性乳腺癌-卵巢癌综合征。
Cancers (Basel). 2024 Nov 30;16(23):4022. doi: 10.3390/cancers16234022.
2
Mutational profiling of 103 unresectable pancreatic ductal adenocarcinomas using EUS-guided fine-needle biopsy.使用超声内镜引导下细针穿刺活检对103例不可切除的胰腺导管腺癌进行突变分析。
Endosc Ultrasound. 2024 May-Jun;13(3):154-164. doi: 10.1097/eus.0000000000000072. Epub 2024 Jul 3.
3
Genome-Wide Analysis to Assess if Heavy Alcohol Consumption Modifies the Association between SNPs and Pancreatic Cancer Risk.全基因组分析评估重度饮酒是否改变 SNP 与胰腺癌风险之间的关联。
Cancer Epidemiol Biomarkers Prev. 2024 Sep 3;33(9):1229-1239. doi: 10.1158/1055-9965.EPI-24-0096.
4
Understanding the Genetic Landscape of Pancreatic Ductal Adenocarcinoma to Support Personalized Medicine: A Systematic Review.了解胰腺导管腺癌的遗传图谱以支持个性化医疗：一项系统综述。
Cancers (Basel). 2023 Dec 21;16(1):56. doi: 10.3390/cancers16010056.
5
The current state of molecular profiling in gastrointestinal malignancies.胃肠恶性肿瘤中分子谱分析的现状。
Biol Direct. 2022 Jun 6;17(1):15. doi: 10.1186/s13062-022-00322-0.
6
Targeting DNA Damage Response and Immune Checkpoint for Anticancer Therapy.靶向 DNA 损伤反应和免疫检查点的抗肿瘤治疗。
Int J Mol Sci. 2022 Mar 17;23(6):3238. doi: 10.3390/ijms23063238.
7
Targeting BRCA and DNA Damage Repair Genes in GI Cancers: Pathophysiology and Clinical Perspectives.靶向胃肠道癌症中的BRCA和DNA损伤修复基因：病理生理学与临床前景
Front Oncol. 2021 Oct 11;11:662055. doi: 10.3389/fonc.2021.662055. eCollection 2021.
8
Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors.胰腺癌流行病学：了解生活方式和遗传风险因素的作用。
Nat Rev Gastroenterol Hepatol. 2021 Jul;18(7):493-502. doi: 10.1038/s41575-021-00457-x. Epub 2021 May 17.
9
Hereditary and Sporadic Pancreatic Ductal Adenocarcinoma: Current Update on Genetics and Imaging.遗传性和散发性胰腺导管腺癌：遗传学和影像学的最新进展。
Radiol Imaging Cancer. 2020 Mar 13;2(2):e190020. doi: 10.1148/rycan.2020190020. eCollection 2020 Mar.
10
An overview of genetic mutations and epigenetic signatures in the course of pancreatic cancer progression.胰腺癌发生发展过程中的遗传突变和表观遗传特征概述。
Cancer Metastasis Rev. 2021 Mar;40(1):245-272. doi: 10.1007/s10555-020-09952-0. Epub 2021 Jan 10.
本文引用的文献
1
Lack of large genomic deletions in BRIP1, PALB2, and FANCD2 genes in BRCA1/2 negative familial breast cancer.BRCA1/2基因阴性的家族性乳腺癌中BRIP1、PALB2和FANCD2基因不存在大片段基因组缺失。
Breast Cancer Res Treat. 2009 Dec;118(3):651-3. doi: 10.1007/s10549-009-0428-8. Epub 2009 Jun 6.
2
High-resolution DNA melting analysis: advancements and limitations.高分辨率DNA熔解分析：进展与局限
Hum Mutat. 2009 Jun;30(6):857-9. doi: 10.1002/humu.20951.
3
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene.外显子组测序确定PALB2为胰腺癌易感基因。
Science. 2009 Apr 10;324(5924):217. doi: 10.1126/science.1171202. Epub 2009 Mar 5.
4
Familial pancreatic cancer.家族性胰腺癌
Arch Pathol Lab Med. 2009 Mar;133(3):365-74. doi: 10.5858/133.3.365.
5
Association of common PALB2 polymorphisms with breast cancer risk: a case-control study.常见PALB2基因多态性与乳腺癌风险的关联：一项病例对照研究
Clin Cancer Res. 2008 Sep 15;14(18):5931-7. doi: 10.1158/1078-0432.CCR-08-0429.
6
Penetrance analysis of the PALB2 c.1592delT founder mutation.PALB2基因c.1592delT始祖突变的外显率分析
Clin Cancer Res. 2008 Jul 15;14(14):4667-71. doi: 10.1158/1078-0432.CCR-08-0210.
7
Analysis of FANCB and FANCN/PALB2 fanconi anemia genes in BRCA1/2-negative Spanish breast cancer families.对BRCA1/2基因阴性的西班牙乳腺癌家族中FANCB和FANCN/PALB2范可尼贫血基因的分析。
Breast Cancer Res Treat. 2009 Feb;113(3):545-51. doi: 10.1007/s10549-008-9945-0. Epub 2008 Feb 27.
8
Identification of a novel truncating PALB2 mutation and analysis of its contribution to early-onset breast cancer in French-Canadian women.在法裔加拿大女性中鉴定一种新的截短型PALB2突变并分析其对早发性乳腺癌的影响。
Breast Cancer Res. 2007;9(6):R83. doi: 10.1186/bcr1828.
9
Fanconi anemia is associated with a defect in the BRCA2 partner PALB2.范可尼贫血与BRCA2的伙伴蛋白PALB2缺陷有关。
Nat Genet. 2007 Feb;39(2):159-61. doi: 10.1038/ng1942. Epub 2006 Dec 31.
10
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.核伴侣蛋白PALB2对BRCA2细胞功能和临床功能的调控
Mol Cell. 2006 Jun 23;22(6):719-729. doi: 10.1016/j.molcel.2006.05.022.
Zotero 插件