瑞典制浆造纸厂工人队列的癌症死亡率。
Cancer mortality in a Swedish cohort of pulp and paper mill workers.
机构信息
Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Göteborg, Sweden.
出版信息
Int Arch Occup Environ Health. 2010 Feb;83(2):123-32. doi: 10.1007/s00420-009-0446-1. Epub 2009 Jul 28.
PURPOSE
To study cancer mortality among Swedish pulp and paper mill workers by main mill pulping process and department, and to present the Swedish part of an international exposure measurements database.
METHODS
A cohort of 18,163 male and 2,290 female workers at four sulfate and four sulfite mills, enrolled from 1939 to 1999, was followed up for mortality during 1952-2001. Standardized mortality ratios (SMRs) relative to the general Swedish population were calculated.
RESULTS
There were 1,340 malignant cases out of 5,898 deaths. Total cancer mortality was not increased in either sulfate or sulfite mill workers, or by gender. Lung cancer mortality was increased among female workers (SMR 1.70, 95% CI 1.04-2.63), especially in paper production, but not among male workers (SMR 0.91, 95% CI 0.79-1.04). Exposure to wood dust and sulfur dioxide frequently exceeded occupational exposure limits.
CONCLUSIONS
Female paper production workers had an increased mortality from lung cancer.
目的
通过主要纸浆生产工艺和部门研究瑞典制浆造纸厂工人的癌症死亡率，并呈现国际暴露测量数据库的瑞典部分。
方法
对 1939 年至 1999 年间在四家硫酸盐浆厂和四家亚硫酸盐浆厂招募的 18163 名男性和 2290 名女性工人进行了队列研究，随访其在 1952 年至 2001 年期间的死亡率。计算了与瑞典总人口相比的标准化死亡率（SMR）。
结果
在 5898 例死亡中，有 1340 例恶性病例。硫酸盐浆厂或亚硫酸盐浆厂的工人或男性工人的总癌症死亡率均未增加。女性工人的肺癌死亡率（SMR 1.70，95%CI 1.04-2.63）增加，尤其是在造纸生产中，但男性工人的肺癌死亡率（SMR 0.91，95%CI 0.79-1.04）没有增加。接触木尘和二氧化硫的情况经常超过职业暴露限值。
结论
女性造纸生产工人的肺癌死亡率增加。
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