Miller B A, Blair A, Reed E J
Division of Cancer Prevention and Control, National Cancer Institute, Bethesda, MD 20892.
Am J Ind Med. 1994 Apr;25(4):537-49. doi: 10.1002/ajim.4700250408.
The addition of 5 years of follow-up and over 411,000 person-years of observation to a cohort of 34,081 men and women employed in U.S. furniture and other related industries allowed the investigation of mortality patterns among women and minority races in addition to white men. A significant excess of pleural mesotheliomas occurred among white men (standardized mortality ratio [SMR] = 3.7, 95% confidence interval [CI] = 1.2-8.7) but could not be linked to a particular type of furniture manufacturing. SMRs for myeloid leukemia and chronic nephritis were elevated among white men employed in the wood furniture industry but were not statistically significant. Males in the black/other race categories in wood furniture plants showed nonsignificant mortality excesses for infectious diseases and cancers of the prostate and colon and rectum. Among white women employed in wood furniture plants, mortality was elevated for cancers of the pancreas and lung during the most recent follow-up period. In metal furniture plants, mortality was raised among men in both race groups for kidney cancer (black/other SMR = 8.0, 95% CI = 1.6-23.2; white SMR = 2.1, 95% CI = 0.4-6.2) and diabetes mellitus (black/other SMR = 2.2, 95% CI = 0.6-5.6; white SMR = 1.8, 95% CI = 0.7-3.9). Stomach cancer mortality was significantly elevated (SMR = 3.3, 95% CI = 1.3-6.8) among white men in metal furniture plants and was of the same magnitude over both the previous and the most recent follow-up periods. Among those working with textiles, SMRs were significantly elevated for leukemia (SMR = 6.1, 95% CI = 1.2-7.8) and cancers of the colon and rectum (SMR = 3.2, 95% CI = 1.3-4.5) for white women. Lung cancer mortality was increased for white men and women in textile operations, but SMRs were not statistically significant. SMRs for a number of other causes of death that were elevated at the end of the earlier follow-up period were not increased during the new follow-up period.
对美国家具及其他相关行业的34,081名男女员工进行了5年的随访,并进行了超过411,000人年的观察,这使得除了白人男性之外,还能够对女性和少数族裔的死亡率模式进行调查。白人男性中胸膜间皮瘤显著超额发生(标准化死亡比[SMR]=3.7,95%置信区间[CI]=1.2-8.7),但无法与特定类型的家具制造联系起来。木质家具行业的白人男性中,髓系白血病和慢性肾炎的标准化死亡比有所升高,但无统计学意义。木质家具厂中黑人/其他种族类别的男性在传染病、前列腺癌以及结肠癌和直肠癌方面显示出非显著性的死亡超额。在木质家具厂工作的白人女性中,在最近的随访期间,胰腺癌和肺癌的死亡率有所升高。在金属家具厂中,两个种族组的男性患肾癌(黑人/其他种族标准化死亡比=8.0,95%置信区间=1.6-23.2;白人标准化死亡比=2.1,95%置信区间=0.4-6.2)和糖尿病(黑人/其他种族标准化死亡比=2.2,95%置信区间=0.6-5.6;白人标准化死亡比=1.8,95%置信区间=0.7-3.9)的死亡率均有所上升。金属家具厂的白人男性胃癌死亡率显著升高(标准化死亡比=3.3,95%置信区间=1.3-6.8),且在之前和最近的随访期间幅度相同。在从事纺织工作的人群中,白人女性白血病(标准化死亡比=6.1,95%置信区间=1.2-7.8)以及结肠癌和直肠癌(标准化死亡比=3.2,95%置信区间=1.3-4.5)的标准化死亡比显著升高。纺织作业中的白人男性和女性肺癌死亡率有所增加,但标准化死亡比无统计学意义。在早期随访期末升高的一些其他死因的标准化死亡比在新的随访期间并未增加。