乙肝病毒衣壳化信号ε的鸭乙肝病毒引物环的1H、13C和15N核磁共振归属
1H, 13C and 15N NMR assignments of Duck HBV primer loop of the encapsidation signal epsilon.
作者信息
van der Werf R M, Girard F C, Nelissen F, Tessari M, Wijmenga S S
机构信息
Department of Biophysical Chemistry, Radboud University Nijmegen, Toernooiveld 1, 6525 ED, Nijmegen, The Netherlands.
出版信息
Biomol NMR Assign. 2008 Dec;2(2):143-5. doi: 10.1007/s12104-008-9106-8. Epub 2008 Aug 19.
The replication of the hepatitis B virus is initiated by binding of the viral reverse transcriptase protein complex to the apical stem loop of the epsilon element to place it next to the primer loop, from which a four nucleotide DNA primer is subsequently synthesized. Here, we present the (1)H/(13)C/(15)N NMR assignments of the bases and sugars of the 37 residues primer loop of Duck HBV epsilon (BMRB-entry 15786).
乙型肝炎病毒的复制始于病毒逆转录酶蛋白复合物与ε元件顶端茎环的结合，使其靠近引物环，随后从引物环合成一个四核苷酸DNA引物。在此，我们展示了鸭乙肝病毒ε（BMRB登录号15786）37个残基引物环中碱基和糖的（1）H/（13）C/（15）N NMR归属。
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