费氏弧菌23.7 kDa同二聚体毒素CcdB的序列特异性1H、15N和13C共振归属
Sequence-specific 1H, 15N and 13C resonance assignments of the 23.7-kDa homodimeric toxin CcdB from Vibrio fischeri.
作者信息
Respondek Michal, Buts Lieven, De Jonge Natalie, Haesaerts Sarah, Loris Remy, Van Melderen Laurence, Wyns Lode, Zangger Klaus
机构信息
Institute of Chemistry/Organic and Bioorganic Chemistry, University of Graz, Heinrichstrasse 28, 8010, Graz, Austria.
出版信息
Biomol NMR Assign. 2009 Jun;3(1):145-7. doi: 10.1007/s12104-009-9161-9. Epub 2009 Apr 3.
CcdB is the toxic component of a bacterial toxin-antitoxin system. It inhibits DNA gyrase (a type II topoisomerase), and its toxicity can be neutralized by binding of its antitoxin CcdA. Here we report the sequential backbone and sidechain (1)H, (15)N and (13)C resonance assignments of CcdB(Vfi) from the marine bacterium Vibrio fischeri. The BMRB accession number is 16135.
CcdB是一种细菌毒素-抗毒素系统的毒性成分。它抑制DNA回旋酶（一种II型拓扑异构酶），其毒性可通过其抗毒素CcdA的结合而中和。在此，我们报告了来自海洋细菌费氏弧菌的CcdB(Vfi)的主链和侧链(1)H、(15)N和(13)C共振归属。BMRB登录号为16135。
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