Lipchock James M, Loria J Patrick
Department of Chemistry, Yale University, Sterling Chemistry Laboratory, New Haven, CT, 06511, USA.
Biomol NMR Assign. 2008 Dec;2(2):219-21. doi: 10.1007/s12104-008-9125-5. Epub 2008 Oct 7.
HisF comprises one half of the heterodimeric protein complex imidazole glycerol phosphate (IGP) synthase responsible for the fifth step of histidine biosynthesis. Here we report backbone and side chain assignments necessary for characterization of protein dynamics involved in the allosteric mechanism of IGP synthase.
HisF是负责组氨酸生物合成第五步的异二聚体蛋白复合物咪唑甘油磷酸(IGP)合酶的一半。在此,我们报告了表征IGP合酶变构机制中涉及的蛋白质动力学所需的主链和侧链归属。