Nakamura H, Hashimoto T, Inoue Y, Inoue K, Akaji H, Sawada S
Department of Radiology, Osaka University, Japan.
Radiat Med. 1990 Sep-Oct;8(5):188-90.
Five patients with large hepatoma (10 cm or more in diameter) underwent transcatheter oily chemoembolization with an emulsion of 100 mg of adriamycin with Lipiodol plus Gelfoam. Myelosuppression related to adriamycin was milder than that associated with bolus injection of the drug, because the drug was released from the emulsion slowly. Partial response was found in one patient, with no change in the others. The duration of survival ranged from four to 16 months (mean, 11.2 months). Response was satisfactory for large hepatoma.
5例大肝癌（直径10厘米或更大）患者接受了经导管油性化疗栓塞术，使用的是100毫克阿霉素与碘油加明胶海绵的乳剂。与阿霉素相关的骨髓抑制比静脉推注该药时更轻，因为药物从乳剂中缓慢释放。1例患者出现部分缓解，其他患者无变化。生存时间为4至16个月（平均11.2个月）。对大肝癌的治疗效果令人满意。
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