Cyrus-David Mfon, King Jason, Bevers Therese, Robinson Emily
Department of Medicine, The University of Texas Medical School, Houston, Texas, USA.
Cancer. 2009 Nov 1;115(21):4907-16. doi: 10.1002/cncr.24541.
: Women at increased risk of breast cancer (BC) are not widely accepting of chemopreventive interventions, and ethnic minorities are underrepresented in related trials. Furthermore, there is no validated instrument to assess the health-seeking behavior of these women with respect to these interventions.
: By using constructs from the Health Belief Model, the authors developed and refined, based on pilot data, the Breast Cancer Risk Reduction Health Belief (BCRRHB) scale using a population of 265 women at increased risk of BC who were largely medically underserved, of low socioeconomic status (SES), and ethnic minorities. Construct validity was assessed using principal components analysis with oblique rotation to extract factors, and generate and interpret summary scales. Internal consistency was determined using Cronbach alpha coefficients.
: Test-retest reliability for the pilot and final data was calculated to be r = 0.85. Principal components analysis yielded 16 components that explained 64% of the total variance, with communalities ranging from 0.50-0.75. Cronbach alpha coefficients for the extracted factors ranged from 0.45-0.77.
: Evidence suggests that the BCRRHB yields reliable and valid data that allows for the identification of barriers and enhancing factors associated with use of breast cancer chemoprevention in the study population. These findings allow for tailoring treatment plans and intervention strategies to the individual. Future research is needed to validate the scale for use in other female populations. Cancer 2009. (c) 2009 American Cancer Society.
乳腺癌（BC）风险增加的女性对化学预防干预措施的接受度并不广泛，且少数族裔在相关试验中的代表性不足。此外，尚无经过验证的工具来评估这些女性在这些干预措施方面的求医行为。
作者运用健康信念模型中的概念，基于试点数据，对265名乳腺癌风险增加的女性进行研究，这些女性大多医疗服务不足、社会经济地位（SES）较低且为少数族裔，据此开发并完善了乳腺癌风险降低健康信念（BCRRHB）量表。使用主成分分析和斜交旋转来提取因素、生成并解释汇总量表，以此评估结构效度。使用克朗巴哈α系数确定内部一致性。
试点数据和最终数据的重测信度计算得出r = 0.85。主成分分析产生了16个成分，解释了总方差的64%，共同度范围为0.50 - 0.75。提取因素的克朗巴哈α系数范围为0.45 - 0.77。
有证据表明，BCRRHB量表能产生可靠且有效的数据，有助于识别研究人群中与使用乳腺癌化学预防相关的障碍和促进因素。这些发现有助于根据个体情况制定治疗计划和干预策略。未来需要开展研究以验证该量表在其他女性人群中的适用性。《癌症》2009年。（c）2009美国癌症协会。
