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另外两例支持先天性大叶性肺气肿非手术治疗的病例。

Two further cases supporting nonsurgical management in congenital lobar emphysema.

作者信息

Kovacevic A, Schmidt K G, Nicolai T, Wisbauer M, Schuster A

机构信息

Department of Paediatric Cardiology and Pneumology, Heinrich Heine University, Düsseldorf, Germany.

出版信息

Klin Padiatr. 2009 Jul-Aug;221(4):232-6. doi: 10.1055/s-0028-1086032.

Abstract

BACKGROUND

For decades, the well-established standard recommended treatment for patients with congenital lobar emphysema (CLE) and respiratory distress has been lobectomy of the affected lobe or lobes, whereas indications for conservative management have been controversially discussed.

PATIENTS/METHODS: Description of the clinical courses including the results of diagnostic procedures and the resulting therapeutic strategies in 2 patients with congenital lobar emphysema. We review the literature on conservatively treated patients with congenital lobar emphysema.

RESULTS

Considering that formerly asserted hypotheses postulating benefits of surgical treatment cannot unambiguously be corroborated from cases in literature, we could show that conservative treatment in patients with congenital lobar emphysema is appropriate in mildly to moderately symptomatic children.

CONCLUSION

Conservative treatment of children with congenital lobar emphysema is an attractive option, whenever justifiable on medical grounds. Our cases may serve as paradigms in decision-making processes in similar cases and - together with the literature review - may be helpful to avoid unnecessary lobectomies in children. Patients treated conservatively will need a close follow-up, and further data on long-term follow-up courses are desirable.

摘要

背景

几十年来,对于患有先天性大叶性肺气肿(CLE)且有呼吸窘迫症状的患者,既定的标准推荐治疗方法一直是切除患叶,而保守治疗的指征一直存在争议。

患者/方法:描述2例先天性大叶性肺气肿患者的临床病程,包括诊断程序的结果及由此产生的治疗策略。我们回顾了关于先天性大叶性肺气肿保守治疗患者的文献。

结果

鉴于以往关于手术治疗益处的假设无法从文献中的病例得到明确证实,我们发现对于轻度至中度症状的先天性大叶性肺气肿患儿,保守治疗是合适的。

结论

只要有医学依据,对先天性大叶性肺气肿患儿进行保守治疗是一个有吸引力的选择。我们的病例可作为类似病例决策过程的范例,并且与文献综述一起,可能有助于避免儿童不必要的肺叶切除术。接受保守治疗的患者需要密切随访,并且需要更多关于长期随访病程的数据。

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