替诺福韦：新适应症。在慢性乙型肝炎中：谨防骨毒性。

Prescrire Int. 2009 Jun;18(101):116.

Tenofovir is more effective than adefovir in reducing viraemia in the short term, but with no histological or serological evidence of improvement. It is also associated with a small increase in gastrointestinal disturbances and exacerbation of hepatitis. Its renal and bone risks also need to be closely monitored.

替诺福韦在短期内降低病毒血症方面比阿德福韦更有效，但没有组织学或血清学改善的证据。它还与胃肠道不适的小幅增加以及肝炎加重有关。其肾脏和骨骼风险也需要密切监测。